5-Hydroxymethyluridine

Base Information

Chemical Name:5-Hydroxymethyluridine
CAS No.:30414-00-7
Molecular Formula:C10H14 N2 O7
Molecular Weight:274.23
Hs Code.:
DSSTox Substance ID:DTXSID00952752
Nikkaji Number:J139.632C
Wikidata:Q82931430
Metabolomics Workbench ID:87089
Mol file:30414-00-7.mol

Synonyms:5-hydroxymethyluridine

Suppliers and Price of 5-Hydroxymethyluridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione 97%
1g
$ 1131.00

Chemenu
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione 97%
1g
$ 1066.00

Total 14 raw suppliers

Chemical Property of 5-Hydroxymethyluridine

Chemical Property:

Melting Point:167-168 °C
Boiling Point:°Cat760mmHg
PKA:9.01±0.10(Predicted)
Flash Point:°C
PSA：145.27000
Density:1.689g/cm³
LogP:-2.94730
XLogP3:-2.3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:274.08010079
Heavy Atom Count:19
Complexity:424

Purity/Quality:

97% ^*data from raw suppliers

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)CO
Isomeric SMILES:C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)CO

Technology Process of 5-Hydroxymethyluridine

There total 10 articles about 5-Hydroxymethyluridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 3816-77-1
2',3'-O-isopropylidene-5-hydroxymethyl-uridine

: 30414-00-7
5-(hydroxymethyl)uridine

Guidance literature:: With water; acetic acid; for 5h; Heating;
DOI:10.1080/15257770008033040

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 58-96-8
uridine

: 30414-00-7
5-(hydroxymethyl)uridine

Guidance literature:: With hydrogenchloride;
DOI:10.1021/ja01519a056

Reference yield:

: 362-43-6
2',3'-O-isopropylideneuridine

: 30414-00-7
5-(hydroxymethyl)uridine

Guidance literature:: Multi-step reaction with 2 steps

1: 31 percent / KOH / H₂O / 48 h / 60 °C

2: AcOH / H₂O / 5 h / Heating

With potassium hydroxide; acetic acid; In water;
DOI:10.1016/j.tetlet.2006.09.083