1H-Indole-1-acetic acid, 2-iodo-, 1,1-diMethylethyl ester

Base Information

Chemical Name:1H-Indole-1-acetic acid, 2-iodo-, 1,1-diMethylethyl ester
CAS No.:206196-82-9
Molecular Formula:C14H16INO2
Molecular Weight:357.18700
Hs Code.:
Mol file:206196-82-9.mol

Synonyms:1H-Indole-1-acetic acid, 2-iodo-, 1,1-dimethylethyl ester;

Suppliers and Price of 1H-Indole-1-acetic acid, 2-iodo-, 1,1-diMethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 1H-Indole-1-acetic acid, 2-iodo-, 1,1-diMethylethyl ester

Chemical Property:

PSA：31.23000
LogP:3.58760

Purity/Quality:: More than 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Indole-1-acetic acid, 2-iodo-, 1,1-diMethylethyl ester

There total 1 articles about 1H-Indole-1-acetic acid, 2-iodo-, 1,1-diMethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5292-43-3
bromoacetic acid tert-butyl ester

: sodium salt of 2-iodoindole

: 206196-82-9
(2-Iodo-indol-1-yl)-acetic acid tert-butyl ester

Guidance literature:: In dimethyl sulfoxide;
DOI:10.1016/S0040-4039(98)00215-9

Reference yield: 33.0%

: 201230-82-2
carbon monoxide

: 21344-90-1
4-(o-chlorophenyl)-1,3-thiazol-2-amine

: 206196-82-9
(2-Iodo-indol-1-yl)-acetic acid tert-butyl ester

: 206196-70-5
{2-[4-(2-Chloro-phenyl)-thiazol-2-ylcarbamoyl]-indol-1-yl}-acetic acid tert-butyl ester

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; tributyl-amine; In N,N-dimethyl acetamide; at 112 - 113 ℃; for 0.166667h;
DOI:10.1016/S0040-4039(98)00215-9

Reference yield:

: 206196-82-9
(2-Iodo-indol-1-yl)-acetic acid tert-butyl ester

: SR 27897

Guidance literature:: Multi-step reaction with 2 steps

1: 33 percent / PdCl₂(PPh₃)2, Bu₃N / N,N-dimethyl-acetamide / 0.17 h / 112 - 113 °C

2: 80 percent / TFA / CH₂Cl₂

With bis-triphenylphosphine-palladium(II) chloride; tributyl-amine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl acetamide;
DOI:10.1016/S0040-4039(98)00215-9