methyl 4-chloro-1H-indazole-3-carboxylate

Base Information

Chemical Name:methyl 4-chloro-1H-indazole-3-carboxylate
CAS No.:932041-14-0
Molecular Formula:C9H7ClN2O2
Molecular Weight:210.61700
Hs Code.:
DSSTox Substance ID:DTXSID80696107
Wikidata:Q82625549
Mol file:932041-14-0.mol

Synonyms:methyl 4-chloro-1H-indazole-3-carboxylate;932041-14-0;4-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER;SCHEMBL4791540;DTXSID80696107;ZTEHEVOAKFIDDI-UHFFFAOYSA-N;SB40026;methyl4-chloro-1H-indazole-3-carboxylate;F76840

Suppliers and Price of methyl 4-chloro-1H-indazole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
4-Chloro-1H-indazole-3-carboxylicacidmethylester 97%
500mg
$ 350.00

J&W Pharmlab
4-Chloro-1H-indazole-3-carboxylicacidmethylester 97%
5g
$ 4880.00

J&W Pharmlab
4-Chloro-1H-indazole-3-carboxylicacidmethylester 97%
1g
$ 1380.00

Crysdot
Methyl4-chloro-1H-indazole-3-carboxylate 95+%
1g
$ 825.00

Chemenu
4-Chloro-1H-indazole-3-carboxylicacidmethylester 95%
1g
$ 779.00

Alichem
Methyl4-chloro-1H-indazole-3-carboxylate
1g
$ 690.10

Total 7 raw suppliers

Chemical Property of methyl 4-chloro-1H-indazole-3-carboxylate

Chemical Property:

PSA：54.98000
LogP:2.00290
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:210.0196052
Heavy Atom Count:14
Complexity:237

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-1H-indazole-3-carboxylicacidmethylester 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=NNC2=C1C(=CC=C2)Cl

Technology Process of methyl 4-chloro-1H-indazole-3-carboxylate

There total 4 articles about methyl 4-chloro-1H-indazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 67-56-1
methanol

: 201230-82-2
carbon monoxide

: 518990-33-5
4-chloro-3-iodo-1H-indazole

: 932041-14-0
methyl 4-chloro-1H-indazole-3-carboxylate

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In dichloromethane; at 50 ℃;

Reference yield: 13.0%

: 932041-14-0
methyl 4-chloro-1H-indazole-3-carboxylate

Guidance literature:

Reference yield:

: 387-45-1
2-chloro-6-fluorobenzaldehyde

: 932041-14-0
methyl 4-chloro-1H-indazole-3-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate / 1,2-dimethoxyethane / Reflux

2: potassium hydroxide; iodine / N,N-dimethyl-formamide / 20 °C

3: 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis-triphenylphosphine-palladium(II) chloride; triethylamine / dichloromethane / 50 °C

With bis-triphenylphosphine-palladium(II) chloride; iodine; hydrazine hydrate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; potassium hydroxide; In 1,2-dimethoxyethane; dichloromethane; N,N-dimethyl-formamide;