Methyl thieno[2,3-c]pyridine-2-carbo×ylate

Base Information

• Chemical Name: Methyl thieno[2,3-c]pyridine-2-carbo×ylate
• CAS No.: 870243-58-6
• Molecular Formula: C₉H₇NO₂S
• Molecular Weight: 193.226
• Hs Code.: 2934999090
• Mol file: 870243-58-6.mol

Synonyms:methyl thieno[2,3-c]pyridine-2-carboxylate;

Chemical Property of Methyl thieno[2,3-c]pyridine-2-carbo×ylate

Chemical Property:

• PSA: 67.43000
• LogP: 2.08290
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Methylthieno[2,3-c]pyridine-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl thieno[2,3-c]pyridine-2-carbo×ylate

There total 7 articles about Methyl thieno[2,3-c]pyridine-2-carbo×ylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

3-fluoropyridine-4-carbaldehyde (40273-47-0) + Methyl thioglycolate (2365-48-2) → methyl thieno[2,3-c]pyridine-2-carboxylate (870243-58-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃;

Reference yield: 80.0%

4-bromo-thieno<2,3-c>pyridine-2-carboxylic acid methyl ester (145325-40-2) → methyl thieno[2,3-c]pyridine-2-carboxylate (870243-58-6)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; triethylamine; In tetrahydrofuran; methanol; for 72h; under 2327.23 Torr; Inert atmosphere;

Reference yield:

methyl 4-chlorothieno[2,3-c]pyridine-2-carboxylate (251996-85-7) → methyl thieno[2,3-c]pyridine-2-carboxylate (870243-58-6)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; at 60 ℃; for 16h; under 3102.97 Torr;

upstream raw materials:

methyl 4-chlorothieno[2,3-c]pyridine-2-carboxylate

3-fluoropyridine-4-carbaldehyde

Methyl thioglycolate

3,5-dibromopyridine

Refernces

• 1、 -. "AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES". . . Retrieved 2013/09/12.
• 2、 -. "AMIDO-BENZYL SULFONE AND SULFONAMIDE DERIVATIVES". . . Retrieved 2013/09/12.