6-methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine

Base Information

Chemical Name:6-methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine
CAS No.:1018473-31-8
Molecular Formula:C16H19N7
Molecular Weight:309.374
Hs Code.:
Mol file:1018473-31-8.mol

Synonyms:6-methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine

Suppliers and Price of 6-methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine 95+%
250mg
$ 337.00

Crysdot
6-Methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine 95+%
1g
$ 842.00

Chemenu
6-Methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine 95%
1g
$ 795.00

Total 4 raw suppliers

Chemical Property of 6-methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine

Chemical Property:

PSA：93.68000
LogP:3.37380

Purity/Quality:

98% ^*data from raw suppliers

6-Methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine

There total 3 articles about 6-methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1018473-30-7
tert-butl 4-methyl-3-(3-methyl-1-(6-methylaminopyrimidin-4-yl)-1H-pyrazol-5-ylamino)phenylcarbamate

: 1018473-31-8
6-methyl-N₁-(3-methyl-1-(6-methylaminopyrimidin-4-yl)-1H-pyrazol-5-yl)benzen-1,3-diamine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;

Reference yield:

: 1018473-22-7
C₈H₈ClN₅

: 1018473-31-8
6-methyl-N₁-(3-methyl-1-(6-methylaminopyrimidin-4-yl)-1H-pyrazol-5-yl)benzen-1,3-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: water; isopropyl alcohol / 4 h / 50 °C / Sealed tube

2: caesium carbonate / palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 48 h / 120 °C / High-pressure tube

3: trifluoroacetic acid / dichloromethane / 4 h / 20 °C

With caesium carbonate; trifluoroacetic acid; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; dichloromethane; water; isopropyl alcohol;

Reference yield:

: 1018473-23-8
(6-(5-amino-3-methylpyrazol-1-yl)pyrimidin-4-yl)methylamine

: 1018473-31-8
6-methyl-N₁-(3-methyl-1-(6-methylaminopyrimidin-4-yl)-1H-pyrazol-5-yl)benzen-1,3-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 48 h / 120 °C / High-pressure tube

2: trifluoroacetic acid / dichloromethane / 4 h / 20 °C

With caesium carbonate; trifluoroacetic acid; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; dichloromethane;