amtizol

Base Information

• Chemical Name: amtizol
• CAS No.: 34283-30-2
• Molecular Formula: C2H4 N4 S
• Molecular Weight: 116.147
• Hs Code.: 2934999090
• Mol file: 34283-30-2.mol

Synonyms:1,2,4-Thiadiazole,3,5-diamino- (7CI,8CI); 3,5-Diamino-1,2,4-thiadiazole; Amtizol; Amtizole

Chemical Property of amtizol

Chemical Property:

• Vapor Pressure: 4.79E-05mmHg at 25°C
• Melting Point: 236-238 °C
• Boiling Point: 349.2°C at 760 mmHg
• PKA: 4.26±0.11(Predicted)
• Flash Point: 165°C
• PSA: 106.06000
• Density: 1.661g/cm³
• LogP: 0.86490
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

95% ^*data from raw suppliers

1,2,4-Thiadiazole-3,5-diamine ^*data from reagent suppliers

Safty Information:

• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of amtizol

There total 4 articles about amtizol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

amidinothiocarbamide (2114-02-5) → 3,5-diamino-1,2,4-thiadiazole (34283-30-2)

Guidance literature:

With dihydrogen peroxide; In methanol; Heating;

DOI:10.1134/S1070363208030237

Reference yield: 78.0%

thiourea (17356-08-0) → 3,5-diamino-1,2,4-thiadiazole (34283-30-2)

Guidance literature:

With bis-{4-methoxy-phenyl}-selenoxyde; In ethanol; for 1h; Ambient temperature;

DOI:10.1246/bcsj.55.641

Reference yield: 75.0%

diphenyl-N-(p-toluenesulfonyl)selenimide (52867-19-3) + thiourea (17356-08-0) → 3,5-diamino-1,2,4-thiadiazole (34283-30-2) + diphenylselenide (1132-39-4) + toluene-4-sulfonamide (70-55-3)

Guidance literature:

In methanol; for 1h; Mechanism; Ambient temperature;

upstream raw materials:

amidinothiocarbamide

diphenyl-N-(p-toluenesulfonyl)selenimide

thiourea

guanylthiourea

Refernces

• 1、 Holyska, Malgorzata,Kubiak, Maria. "Products of the oxidation of 1-(di-amino-methyl-ene)thio-urea with hydrogen peroxide". . p. o609-o612. Retrieved 2008.
• 2、 Chande, Madhukar S.,Carvalho, Peter V. R.. "A facile synthesis of novel nitrogen-sulphur heterocycles containing the amidino moiety and their antimicrobial activity - Part I". . p. 378 - 384. Retrieved 2007/10/03.