1-Piperidinecarboxylic acid, 5-aMino-2-Methyl-, phenylMethyl est

Base Information

Chemical Name:1-Piperidinecarboxylic acid, 5-aMino-2-Methyl-, phenylMethyl est
CAS No.:1207853-72-2
Molecular Formula:C14H20N2O2
Molecular Weight:248.325
Hs Code.:
Mol file:1207853-72-2.mol

Synonyms:1-Piperidinecarboxylic acid, 5-aMino-2-Methyl-, phenylMethyl est;1-Piperidinecarboxylic acid, 5-aMino-2-Methyl-, phenylMethyl ester, (2S,5R)-

Suppliers and Price of 1-Piperidinecarboxylic acid, 5-aMino-2-Methyl-, phenylMethyl est

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2R,5R)-Benzyl5-amino-2-methylpiperidine-1-carboxylate
2.5mg
$ 165.00

Crysdot
(2R,5R)-Benzyl5-amino-2-methylpiperidine-1-carboxylate 95+%
100mg
$ 483.00

ChemScene
Benzyl(2R,5R)-5-amino-2-methylpiperidine-1-carboxylate
100mg
$ 474.00

American Custom Chemicals Corporation
(2R,5R)-5-AMINO-2-METHYLPIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 95.00%
5MG
$ 503.81

Total 8 raw suppliers

Chemical Property of 1-Piperidinecarboxylic acid, 5-aMino-2-Methyl-, phenylMethyl est

Chemical Property:

Boiling Point:373.2±42.0 °C(Predicted)
PKA:10.34±0.40(Predicted)
PSA：55.56000
Density:1.111±0.06 g/cm3(Predicted)
LogP:2.77300

Purity/Quality:

99%, ^*data from raw suppliers

(2R,5R)-Benzyl5-amino-2-methylpiperidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (2R,5R)-Benzyl 5-amino-2-methylpiperidine-1-carboxylate is a reactant used in the preparation of pyridylamino-nitrile-piperidinyl Orexin receptor antagonists.

Technology Process of 1-Piperidinecarboxylic acid, 5-aMino-2-Methyl-, phenylMethyl est

There total 8 articles about 1-Piperidinecarboxylic acid, 5-aMino-2-Methyl-, phenylMethyl est which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1612786-30-7
(2R,5R)-benzyl 5-azido-2-methylpiperidine-1-carboxylate

: 1207853-72-2,1207947-49-6
benzyl (2R,5R)-5-amino-2-methyl-piperidine-1-carboxylate

Guidance literature:: With trimethylphosphane; In tetrahydrofuran; toluene; for 0.333333h;

Reference yield:

: rac-(2S,5S)-benzyl 5-((tert-butoxycarbonyl)amino)-2-methylpiperidine-1-carboxylate

: 1207853-72-2,1207947-49-6
benzyl (2R,5R)-5-amino-2-methyl-piperidine-1-carboxylate

: 1207947-49-6
benzyl (2S,5S)-5-amino-2-methyl-piperidine-1-carboxylate

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 15 ℃; for 1h;

Reference yield:

: 1612786-29-4
(2R,5S)-benzyl 2-methyl-5-((methylsulfonyl)oxy)piperidine-1-carboxylate

: 1207853-72-2,1207947-49-6
benzyl (2R,5R)-5-amino-2-methyl-piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / N,N-dimethyl-formamide / 85 °C

2: trimethylphosphane / tetrahydrofuran; toluene / 0.33 h

With sodium azide; trimethylphosphane; In tetrahydrofuran; N,N-dimethyl-formamide; toluene;