Methyl 2-Bromo-5-sulfamoylbenzoate

Base Information

• Chemical Name: Methyl 2-Bromo-5-sulfamoylbenzoate
• CAS No.: 924867-88-9
• Molecular Formula: C₈H₈BrNO₄S
• Molecular Weight: 294.126
• Hs Code.: 2935009090
• Mol file: 924867-88-9.mol

Synonyms:Benzoic acid, 5-(aminosulfonyl)-2-bromo-, methyl ester; methyl 2-bromo-5-sulfamoylbenzoate

Chemical Property of Methyl 2-Bromo-5-sulfamoylbenzoate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 433.622°C at 760 mmHg
• Flash Point: 216.047°C
• PSA: 94.84000
• Density: 1.705g/cm³
• LogP: 2.66420

Purity/Quality:

98%min ^*data from raw suppliers

Methyl 2-bromo-5-sulfamoylbenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 2-Bromo-5-sulfamoylbenzoate

There total 3 articles about Methyl 2-Bromo-5-sulfamoylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + C7H6BrNO4S (22361-61-1) → C8H8BrNO4S (924867-88-9)

Guidance literature:

With thionyl chloride; at 20 ℃;

Reference yield:

2-bromobenzoic-acid (88-65-3) → C8H8BrNO4S (924867-88-9)

Guidance literature:

Multi-step reaction with 3 steps

1: chlorosulfonic acid / 135 - 140 °C

2: ammonia / Cooling with ice

3: thionyl chloride / 20 °C

With chlorosulfonic acid; thionyl chloride; ammonia;

Reference yield:

2-bromo-5-(chlorosulfonyl)benzoic acid (3285-31-2) → C8H8BrNO4S (924867-88-9)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonia / Cooling with ice

2: thionyl chloride / 20 °C

With thionyl chloride; ammonia;

upstream raw materials:

methanol

C₇H₆BrNO₄S

2-bromobenzoic-acid

2-bromo-5-(chlorosulfonyl)benzoic acid

Refernces