(2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid

Base Information

Chemical Name:(2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid
CAS No.:62023-65-8
Molecular Formula:C15H21NO5
Molecular Weight:295.335
Hs Code.:2924299090
DSSTox Substance ID:DTXSID40444505
Nikkaji Number:J1.937.693A
Wikidata:Q82262656
Mol file:62023-65-8.mol

Synonyms:62023-65-8;(2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid;N-Boc-(2S,3R)-2-hydroxy-3-amino-4-phenylbutanoic acid;(2S,3R)-3-((tert-Butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoic acid;Boc-(2S,3R)-AHPA;(2S,3R)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoic acid;(2S,3R)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-4-phenylbutanoic acid;MFCD00057841;SCHEMBL825622;DTXSID40444505;AKOS016843855;AS-72743;CS-0134071;EN300-12447022;(2S,3R)-2-Hydroxy-3-(tert-butoxycarbonylamino)-4-phenylbutanoic acid;(2S,3R)-3-((tert-Butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoicacid;(2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid, >=98.0% (TLC);(2S,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutanoic acid

Suppliers and Price of (2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AHH
N-Boc-(2S,3R)-2-hydroxy-3-amino-4-phenylbutanoicacid 98%
0.5g
$ 305.00

Alfa Aesar
(2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid, 97%
250mg
$ 342.00

Alfa Aesar
(2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid, 97%
1g
$ 968.00

Alichem
(2S,3R)-3-((tert-Butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoicacid
1g
$ 646.84

American Custom Chemicals Corporation
N-BOC-(2S,3R)-2-HYDROXY-3-AMINO-4-PHENYLBUTANOIC ACID 95.00%
1G
$ 1033.73

American Custom Chemicals Corporation
N-BOC-(2S,3R)-2-HYDROXY-3-AMINO-4-PHENYLBUTANOIC ACID 95.00%
5G
$ 2656.50

American Custom Chemicals Corporation
N-BOC-(2S,3R)-2-HYDROXY-3-AMINO-4-PHENYLBUTANOIC ACID 95.00%
1MG
$ 213.15

Chemenu
Boc-(2S,3R)-AHPA 95%
1g
$ 729.00

Crysdot
(2S,3R)-3-((tert-Butoxycarbonyl)amino)-2-hydroxy-4-phenylbutanoicacid 95+%
1g
$ 772.00

Medical Isotopes, Inc.
N-Boc-(2S,3R)-2-hydroxy-3-amino-4-phenylbutanoicacid
1 g
$ 695.00

Total 17 raw suppliers

Chemical Property of (2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid

Chemical Property:

Boiling Point:499.1±45.0 °C(Predicted)
PKA:3.57±0.17(Predicted)
PSA：95.86000
Density:1 +-.0.06 g/cm3(Predicted)
LogP:1.95880
Storage Temp.:−20°C
Water Solubility.:Insoluble in water. Soluble in organic solvents.
XLogP3:1.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:295.14197277
Heavy Atom Count:21
Complexity:358

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Boc-(2S,3R)-2-hydroxy-3-amino-4-phenylbutanoicacid 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=CC=C1)C(C(=O)O)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@H](CC1=CC=CC=C1)[C@@H](C(=O)O)O
Uses (2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid, is used as a novel protected amino acid for the preparation of bestatin and analogs.

Technology Process of (2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid

There total 44 articles about (2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 59554-14-2
(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoic acid

: 62023-65-8
(2S,3R)-3-[(tert-butoxycarbonyl) amino]-2-hydroxy-4-phenyl-butanoic acid

Guidance literature:: With potassium carbonate; In tetrahydrofuran; water; at 0 - 20 ℃; for 1h;

Reference yield: 79.0%

: 81926-51-4
N-(tert-butyloxycarbonyl)-(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoic acid methyl ester

: 62023-65-8
(2S,3R)-3-[(tert-butoxycarbonyl) amino]-2-hydroxy-4-phenyl-butanoic acid

Guidance literature:: With sodium carbonate; In methanol; water; at 20 ℃; for 12h;
DOI:10.1016/S0040-4039(03)01799-4

Reference yield: 45.0%

: 773837-37-9
sodium cyanide

: 24424-99-5
di-tert-butyl dicarbonate

: 18942-49-9
Boc-D-Phe-OH

: 62023-65-8
(2S,3R)-3-[(tert-butoxycarbonyl) amino]-2-hydroxy-4-phenyl-butanoic acid

Guidance literature:: Boc-D-Phe-OH; With sodium hydrogensulfite; In water; ethyl acetate; for 10h;

sodium cyanide; In water; ethyl acetate; at 20 ℃;

di-tert-butyl dicarbonate;