2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanol

Base Information

Chemical Name:2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanol
CAS No.:306298-23-7
Molecular Formula:C10H11F3O2
Molecular Weight:220.191
Hs Code.:2909499000
DSSTox Substance ID:DTXSID10440372
Mol file:306298-23-7.mol

Synonyms:2-methoxy-1-(4-(trifluoromethyl)phenyl)ethanol;306298-23-7;2-methoxy-1-[4-(trifluoromethyl)phenyl]ethanol;SCHEMBL6677209;DTXSID10440372;RTAHBTGTKHXJQE-UHFFFAOYSA-N;AKOS012086066;FT-0652623;A820460;2-methoxy-1-[4-(trifluoromethyl)phenyl]ethan-1-ol

Suppliers and Price of 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-METHOXY-1-(4-(TRIFLUOROMETHYL)PHENYL)ETHANOL 95.00%
5G
$ 3054.98

American Custom Chemicals Corporation
2-METHOXY-1-(4-(TRIFLUOROMETHYL)PHENYL)ETHANOL 95.00%
250MG
$ 654.15

Total 8 raw suppliers

Chemical Property of 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanol

Chemical Property:

PSA：29.46000
LogP:2.38520
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:220.07111408
Heavy Atom Count:15
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

2-METHOXY-1-(4-(TRIFLUOROMETHYL)PHENYL)ETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCC(C1=CC=C(C=C1)C(F)(F)F)O

Technology Process of 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanol

There total 3 articles about 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 26771-69-7
2-methoxy-1-(4-(trifluoromethyl)phenyl)ethan-1-one

: 306298-23-7
1-(4-(trifluoromethyl)phenyl)-2-methoxyethan-1-ol

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 - 20 ℃;
DOI:10.1002/chem.202000251

Reference yield: 55.0%

: 67-56-1
methanol

: 111991-14-1
2-(4-trifluoromethylphenyl)oxirane

: 306298-23-7
1-(4-(trifluoromethyl)phenyl)-2-methoxyethan-1-ol

Guidance literature:: With sodium methylate; at 20 ℃; for 24h;

Reference yield:

: 402-43-7
p-trifluoromethylphenyl bromide

: 306298-23-7
1-(4-(trifluoromethyl)phenyl)-2-methoxyethan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / diethyl ether; hexane / 0.33 h / 0 °C

1.2: 2 h / 20 °C

2.1: sodium tetrahydroborate / methanol / 0 - 20 °C

With sodium tetrahydroborate; n-butyllithium; In methanol; diethyl ether; hexane;
DOI:10.1002/chem.202000251