2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone

Base Information

Chemical Name:2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone
CAS No.:26771-69-7
Molecular Formula:C10H9F3O2
Molecular Weight:218.175
Hs Code.:2914700090
DSSTox Substance ID:DTXSID80436540
Nikkaji Number:J1.430.570J
Wikidata:Q72486324
Mol file:26771-69-7.mol

Synonyms:26771-69-7;2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone;2-Methoxy-1-(4'-trifluoromethyl)phenylethanone;2-methoxy-1-[4-(trifluoromethyl)phenyl]ethanone;SCHEMBL3391803;DTXSID80436540;AC-578;AKOS012085133;FT-0653387;4'-(Trifluoromethyl)-alpha-methoxyacetophenone;F80202;A818596

Suppliers and Price of 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone
1 g
$ 592.00

Crysdot
2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone 95+%
5g
$ 628.00

American Custom Chemicals Corporation
2-METHOXY-1-(4'-TRIFLUOROMETHYL)PHENYLETHANONE 95.00%
1G
$ 479.85

Acrotein
2-Methoxy-1-(4-trifluoromethylphenyl)-ethanone 97%
0.5g
$ 275.00

Total 31 raw suppliers

Chemical Property of 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone

Chemical Property:

Appearance/Colour:White to light yellow crystal powder
Melting Point:50-52 °C
Boiling Point:259.282 °C at 760 mmHg
Flash Point:107.352 °C
PSA：26.30000
Density:1.23 g/cm³
LogP:2.53450
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:218.05546401
Heavy Atom Count:15
Complexity:217

Purity/Quality:

97% ^*data from raw suppliers

2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCC(=O)C1=CC=C(C=C1)C(F)(F)F

Technology Process of 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone

There total 9 articles about 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 116332-61-7
N-methoxy-N-methyl-4-trifluoromethylbenzamide

: 107-30-2
chloromethyl methyl ether

: 26771-69-7
2-methoxy-1-(4-(trifluoromethyl)phenyl)ethan-1-one

Guidance literature:: With 4,4'-di-tert-butylbiphenyl; lithium; In tetrahydrofuran; mineral oil; at -78 ℃; for 2.5h; Inert atmosphere; Schlenk technique;
DOI:10.1039/c6cc03532a

Reference yield: 73.0%

: 402-44-8
4-Fluorobenzotrifluoride

: 132289-57-7
(N-methyl-N-methoxy)methoxyacetamide

: 26771-69-7
2-methoxy-1-(4-(trifluoromethyl)phenyl)ethan-1-one

Guidance literature:: 4-Fluorobenzotrifluoride; With n-butyllithium; In tetrahydrofuran; hexane; for 0.0833333h;

(N-methyl-N-methoxy)methoxyacetamide; In tetrahydrofuran; at 20 ℃; for 4h;
DOI:10.1021/jm0304515

Reference yield: 71.0%

: 455-18-5
4-CF₃C₆H₄CN

: 4009-98-7
(methoxymethyl)triphenylphosphonium chloride

: 26771-69-7
2-methoxy-1-(4-(trifluoromethyl)phenyl)ethan-1-one

Guidance literature:: (methoxymethyl)triphenylphosphonium chloride; With phenyllithium; In tetrahydrofuran; at 0 ℃; for 0.166667h;

4-CF₃C₆H₄CN; In tetrahydrofuran; at 20 ℃; for 2h;

With water; In tetrahydrofuran;
DOI:10.1055/s-1999-3580