2,6-Dichloro-4-methoxybenzaldehyde

Base Information

• Chemical Name: 2,6-Dichloro-4-methoxybenzaldehyde
• CAS No.: 82772-93-8
• Molecular Formula: C8H6Cl2O2
• Molecular Weight: 205.04
• Hs Code.: 2913000090
• European Community (EC) Number: 810-231-6
• Mol file: 82772-93-8.mol

Synonyms:2,6-dichloro-4-methoxybenzaldehyde;82772-93-8;2,6-dichloro-4-methoxy-benzaldehyde;Benzaldehyde, 2,6-dichloro-4-methoxy-;SCHEMBL207231;VOYUCTPCAWSYTF-UHFFFAOYSA-N;AMY28855;MFCD12024958;AKOS022693183;AB93177;CK-0714;CS-0150479;EN300-118532;A856440;Z1269136118

Chemical Property of 2,6-Dichloro-4-methoxybenzaldehyde

Chemical Property:

• PSA: 26.30000
• LogP: 2.81450
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 203.9744848
• Heavy Atom Count: 12
• Complexity: 151

Purity/Quality:

97% ^*data from raw suppliers

2,6-Dichloro-4-methoxybenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C(=C1)Cl)C=O)Cl

Technology Process of 2,6-Dichloro-4-methoxybenzaldehyde

There total 10 articles about 2,6-Dichloro-4-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,6-dichloro-4-hydroxybenzaldehyde (60964-09-2) + methyl iodide (74-88-4) → 2,6-dichloro-4-methoxy-benzaldehyde (82772-93-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

Reference yield: 94.0%

(2,6-dichloro-4-methoxy-phenyl)-methanol (86111-47-9) → 2,6-dichloro-4-methoxy-benzaldehyde (82772-93-8)

Guidance literature:

With manganese(IV) oxide; In benzene; for 18h; Heating;

DOI:10.1021/jm00396a012

Reference yield: 28.0%

Dichloromethyl methyl ether (4885-02-3) + 3,5-dichloroanisole (33719-74-3) → 2,6-dichloro-4-methoxy-benzaldehyde (82772-93-8)

Guidance literature:

With tin(IV) chloride; In dichloromethane; 1.) 0 deg C, 30 min, 2.) RT, 3 h;

DOI:10.1021/jm00386a008

upstream raw materials:

Dichloromethyl methyl ether

3,5-dichloroanisole

(2,6-dichloro-4-methoxy-phenyl)-methanol

formaldehyd

Downstream raw materials:

[1-(2,6-Dichloro-4-methoxy-phenyl)-meth-(Z)-ylidene]-propyl-amine

C₃₀H₂₄Cl₄N₂O₄

1-(2,6-dichloro-4-methoxyphenyl)-2-(2-fluoro-4-methoxyphenyl)ethene

(E/Z)-1-(2-chloro-4-methoxyphenyl)-2-(2,6-dichloro-4-methoxyphenyl)ethene