3-Bromo-5-methoxyphenol

Base Information

• Chemical Name: 3-Bromo-5-methoxyphenol
• CAS No.: 855400-66-7
• Molecular Formula: C7H7BrO2
• Molecular Weight: 203.035
• Hs Code.: 2909500000
• Mol file: 855400-66-7.mol

Synonyms:phenol, 3-bromo-5-methoxy-

Chemical Property of 3-Bromo-5-methoxyphenol

Chemical Property:

• Vapor Pressure: 0.00269mmHg at 25°C
• Melting Point: 102 °C
• Boiling Point: 277.4°C at 760 mmHg
• PKA: 8.63±0.10(Predicted)
• Flash Point: 121.5°C
• PSA: 29.46000
• Density: 1.585g/cm³
• LogP: 2.16330
• Storage Temp.: Room temperature.

Purity/Quality:

97% ^*data from raw suppliers

3-Bromo-5-methoxyphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Bromo-5-methoxyphenol

There total 3 articles about 3-Bromo-5-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-bromo-3,5-dimethoxybenzene (20469-65-2) → 3-bromo-5-methoxyphenol (855400-66-7)

Guidance literature:

With 2-(diethylamino)ethanethiol hydrochloride; sodium t-butanolate; In N,N-dimethyl-formamide; at 138 ℃; for 3h;

Reference yield: 71.0%

1-bromo-3,5-dimethoxybenzene (20469-65-2) → 5-bromoresorcinol (106120-04-1) + 3-bromo-5-methoxyphenol (855400-66-7)

Guidance literature:

With boron tribromide; In dichloromethane; at -78 - 20 ℃; for 18h; Overall yield = 96 percent; Inert atmosphere;

DOI:10.3762/BJOC.17.22

Reference yield:

3-bromo-5-methoxyaminobenzene (16618-68-1) → 3-bromo-5-methoxyphenol (855400-66-7)

Guidance literature:

Diazotization_.Verkochen mit verd. Schwefelsaeure;

upstream raw materials:

3-bromo-5-methoxyaminobenzene

1-bromo-3,5-dimethoxybenzene

Downstream raw materials:

5-bromoresorcinol

(2-bromo-4-hydroxy-6-methoxy-phenyl)-glyoxylic acid ethyl ester

1-bromo-3,5-dimethoxybenzene

1-Bromo-3-methoxy-5-[(1S)-2-methoxy-1-methylethoxy]benzene