3-chloro-N-methylpyridin-2-amine

Base Information

Chemical Name:3-chloro-N-methylpyridin-2-amine
CAS No.:468718-67-4
Molecular Formula:C6H7ClN2
Molecular Weight:142.59
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80592897
Nikkaji Number:J1.734.589C
Wikidata:Q82487254
Mol file:468718-67-4.mol

Synonyms:3-chloro-N-methylpyridin-2-amine;468718-67-4;2-Pyridinamine,3-chloro-N-methyl-(9CI);(3-CHLORO-PYRIDIN-2-YL)-METHYLAMINE;MFCD11122502;SCHEMBL9909388;DTXSID80592897;2-Pyridinamine, 3-chloro-N-methyl-;STK505497;AKOS000321262;DS-6988;SB52598;N-(3-chloropyridin-2-yl)-N-methylamine;SY084981;DB-270970;CS-0151037;W16401;EN300-1264147;A847029

Suppliers and Price of 3-chloro-N-methylpyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Chloro-N-methylpyridin-2-amine
100mg
$ 65.00

SynQuest Laboratories
3-Chloro-N-methylpyridin-2-amine 95%
5 g
$ 1064.00

SynQuest Laboratories
3-Chloro-N-methylpyridin-2-amine 95%
1 g
$ 360.00

Matrix Scientific
3-Chloro-N-methylpyridin-2-amine
500mg
$ 111.00

Crysdot
3-Chloro-N-methylpyridin-2-amine 95+%
5g
$ 508.00

Crysdot
3-Chloro-N-methylpyridin-2-amine 95+%
10g
$ 771.00

Chemenu
3-Chloro-N-methylpyridin-2-amine 95%
25g
$ 1421.00

Chemenu
3-Chloro-N-methylpyridin-2-amine 95%
10g
$ 728.00

Chemenu
3-Chloro-N-methylpyridin-2-amine 95%
5g
$ 480.00

Chemenu
3-Chloro-N-methylpyridin-2-amine 95%
1g
$ 174.00

Total 10 raw suppliers

Chemical Property of 3-chloro-N-methylpyridin-2-amine

Chemical Property:

PSA：24.92000
LogP:1.84970
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:142.0297759
Heavy Atom Count:9
Complexity:87.1

Purity/Quality:

97% ^*data from raw suppliers

3-Chloro-N-methylpyridin-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=C(C=CC=N1)Cl

Technology Process of 3-chloro-N-methylpyridin-2-amine

There total 5 articles about 3-chloro-N-methylpyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 468718-63-0
N-(3-chloro-4-trimethylsilylpyridin-2-yl)-N-methylamine

: 468718-67-4
N-(3-chloropyridin-2-yl)-N-methylamine

Guidance literature:: With 4 A molecular sieve; tetrabutyl ammonium fluoride; In tetrahydrofuran; for 1h;
DOI:10.1016/S0040-4020(02)00310-1

Reference yield: 70.0%

: 2402-77-9
2,3-dichloro-pyridine

: 74-89-5
methylamine

: 468718-67-4
N-(3-chloropyridin-2-yl)-N-methylamine

Guidance literature:: at 125 ℃; Sealed tube;

Reference yield:

: N-(3-chloro-2-pyridyl)-2,2-dimethylpropanamide

: 468718-67-4
N-(3-chloropyridin-2-yl)-N-methylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / LDA / tetrahydrofuran / 2 h / -75 - 20 °C

2: 100 percent / aq. HCl / Heating

3: 79 percent / NaH / tetrahydrofuran / -40 - 20 °C

4: 80 percent / TBAF; 4 Angstroem molecular sieves / tetrahydrofuran / 1 h

With hydrogenchloride; 4 A molecular sieve; tetrabutyl ammonium fluoride; sodium hydride; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1016/S0040-4020(02)00310-1