2,6-Dibromo phenylacetic acid

Base Information

• Chemical Name: 2,6-Dibromo phenylacetic acid
• CAS No.: 901310-02-9
• Molecular Formula: C8H6Br2O2
• Molecular Weight: 293.942
• Hs Code.: 2916399090
• Mol file: 901310-02-9.mol

Synonyms:2-(2,6-dibromophenyl)acetic acid;

Chemical Property of 2,6-Dibromo phenylacetic acid

Chemical Property:

• Boiling Point: 370.5±27.0 °C(Predicted)
• PKA: 3.80±0.10(Predicted)
• PSA: 37.30000
• Density: 1.969±0.06 g/cm3(Predicted)
• LogP: 2.83870
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98.5% ^*data from raw suppliers

2-(2,6-Dibromophenyl)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-Dibromo phenylacetic acid

There total 2 articles about 2,6-Dibromo phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-(2,6-dibromophenyl)acetonitrile (67197-53-9) → 2-(2,6-dibromophenyl)acetic acid (901310-02-9)

Guidance literature:

With sulfuric acid; at 170 ℃;

DOI:10.1016/j.tetlet.2006.04.103

Reference yield:

2,6-dibromobenzyl bromide (93701-32-7) → 2-(2,6-dibromophenyl)acetic acid (901310-02-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / ethanol; H₂O / Heating

2: 90 percent / aq. H₂SO₄ / 170 °C

With sulfuric acid; In ethanol; water;

DOI:10.1016/j.tetlet.2006.04.103

Reference yield: 86.0%

2-(2,6-dibromophenyl)acetic acid (901310-02-9) → methyl 2-(2,6-dibromophenyl)acetate

Guidance literature:

With thionyl chloride; In methanol; at 0 - 60 ℃; for 3h;

upstream raw materials:

2-(2,6-dibromophenyl)acetonitrile

2,6-dibromobenzyl bromide

Downstream raw materials:

N-methyl-2,6-dibromophenylacetamide

Refernces