TsDACH RuCl(p-cyMene)

Base Information

• Chemical Name: TsDACH RuCl(p-cyMene)
• CAS No.: 192057-12-8
• Molecular Formula: C23H33ClN2O2RuS
• Mol file: 192057-12-8.mol

Synonyms:TsDACH RuCl(p-cyMene);[N-[(1S,2S)-2-(Amino)cyclohexyl]-4-methylbenzenesulfonamidato]chloro[(1,2,3,4,5,6-eta)-1-methyl-4-(1-methylethyl)benzene]ruthenium;N-[(1S,2S)-2-(amino-κN)cyclohexyl]-4-methylbenzenesulfonamidato-κN]chloro[(1,2,3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene]-Ruthenium

Chemical Property of TsDACH RuCl(p-cyMene)

Chemical Property:

Purity/Quality:

99%+, ^*data from raw suppliers

[((1S,2S)-2-Aminocyclohexyl)[(4-methylphenyl)sulfonyl]amido](chloro)(η6-p-cymene)ruthenium ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of TsDACH RuCl(p-cyMene)

There total 1 articles about TsDACH RuCl(p-cyMene) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (52462-29-0) + N-[(1S,2S)-2-aminocyclohexan-1-yl]-4-methylbenzenesulfonamide (174291-97-5,58825-94-8) → [chloro((S,S)-trans-N-(p-toluenesulfonyl)-1,2-diaminecyclohexane)(η6-(p-isopropyltoluene))ruthenium(II)] (192057-12-8,213603-12-4)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/anie.201611291

Reference yield: 31.0%

dichloromethane (75-09-2) + RuCl[κ2(N,N')-(S,S)-p-CH3C6H4SO2NCH(CH2)4CHNH2](η6-p-cymene) (192057-12-8,213603-12-4) + dimethyl zinc(II) (544-97-8) → Ru(CH3)[κ2(N,N')-(S,S)-TsN(C6H10)NH2](η6-p-cymene)*0.5CH2Cl2

Guidance literature:

In tetrahydrofuran; under Ar atm. to soln. Ru complex in THF ZnMe2 was added at 0°C and stirred at this temp. for 5 h; soln. was filtered through alumina, solvent was removed in vacuo, recrystn. from CH2Cl2-Et2O; elem. anal.;

DOI:10.1016/j.jorganchem.2006.04.047

upstream raw materials:

[ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂

N-[(1S,2S)-2-aminocyclohexan-1-yl]-4-methylbenzenesulfonamide

Refernces

• 1、 Canivet, Jerome,Labat, Gael,Stoeckli-Evans, Helen,Suess-Fink, Georg. "Water-soluble arene ruthenium complexes containing a trans-1,2- diaminocyclohexane ligand as enantioselective transfer hydrogenation catalysts in aqueous solution". . p. 4493 - 4500. Retrieved 2007/10/03.