4-Methyl-n3-(4-pyridin-3-yl-thiazol-2-yl)-benzene-1,3-diaMine

Base Information

Chemical Name:4-Methyl-n3-(4-pyridin-3-yl-thiazol-2-yl)-benzene-1,3-diaMine
CAS No.:660837-08-1
Molecular Formula:C15H14N4S
Molecular Weight:282.369
Hs Code.:
Mol file:660837-08-1.mol

Synonyms:MASIT-007;2-(2-Methyl-5-aminophenylamino)-4-(3-pyridyl)thiazole;6-Methyl-N1-[4-(3-pyridyl)-2-thiazolyl]-1,3-benzenediamine;4-Methyl-N3-[4-(3-pyridinyl)-2-thiazolyl]-1,3-benzenediamine;6-methyl-N1-(5-(pyridin-3-yl)thiazol-2-yl)benzene-1,3-diamine;4-Methyl-n3-(4-pyridin-3-yl-thiazol-2-yl)-benzene-1,3-diaMine;1,3-Benzenediamine, 4-methyl-N3-[4-(3-pyridinyl)-2-thiazolyl]-

Suppliers and Price of 4-Methyl-n3-(4-pyridin-3-yl-thiazol-2-yl)-benzene-1,3-diaMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Methyl-N1-(4-(pyridin-3-yl)thiazol-2-yl)benzene-1,3-diamine 97%
250mg
$ 352.00

Total 21 raw suppliers

Chemical Property of 4-Methyl-n3-(4-pyridin-3-yl-thiazol-2-yl)-benzene-1,3-diaMine

Chemical Property:

Boiling Point:509.391 °C at 760 mmHg
PKA:4.69±0.10(Predicted)
Flash Point:261.87 °C
PSA：95.30000
Density:1.312 g/cm³
LogP:3.84240

Purity/Quality:

98%, ^*data from raw suppliers

6-Methyl-N1-(4-(pyridin-3-yl)thiazol-2-yl)benzene-1,3-diamine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Methyl-n3-(4-pyridin-3-yl-thiazol-2-yl)-benzene-1,3-diaMine

There total 9 articles about 4-Methyl-n3-(4-pyridin-3-yl-thiazol-2-yl)-benzene-1,3-diaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 2-[(2-methyl-5-tert-butoxycarbonylaminophenyl)amino]-4-(3-pyridyl)thiazole

: 660837-08-1
N₁-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]-6-methyl-1,3-phenylenediamine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

Reference yield: 85.0%

: 1048007-94-8
N-(2-methyl-5-nitrophenyl)-4-(pyridin-3-yl)thiazol-2-amine

: 660837-08-1
N₁-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]-6-methyl-1,3-phenylenediamine

Guidance literature:: With hydrogen; nickel; In tetrahydrofuran; methanol; at 40 - 45 ℃; for 2h; under 3677.86 Torr;

Reference yield:

: N-(2-methyl-5-nitrophenyl)-4-bromothiazol-2-amine

: 660837-08-1
N₁-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]-6-methyl-1,3-phenylenediamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; bis-triphenylphosphine-palladium(II) chloride / water; 1,4-dioxane / 10 h / Inert atmosphere; Reflux

2: tin(ll) chloride; hydrogenchloride / water / 6 h / 20 °C / Cooling with ice

With hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; tin(ll) chloride; In 1,4-dioxane; water;