3-(Bromoacetyl)pyridine hydrobromide

Base Information

• Chemical Name: 3-(Bromoacetyl)pyridine hydrobromide
• CAS No.: 17694-68-7
• Molecular Formula: C7H7Br2NO
• Molecular Weight: 280.947
• Hs Code.: 2933399090
• European Community (EC) Number: 241-692-6
• NSC Number: 63193
• DSSTox Substance ID: DTXSID70170224
• Mol file: 17694-68-7.mol

Synonyms:3-(2-bromoacetyl)pyridine;3-(2-bromoacetyl)pyridine hydrobromide

Chemical Property of 3-(Bromoacetyl)pyridine hydrobromide

Chemical Property:

• Appearance/Colour: White crystalline solid
• Vapor Pressure: 0.00497mmHg at 25°C
• Melting Point: 192 °C
• Boiling Point: 275.9 °C at 760 mmHg
• Flash Point: 120.6 °C
• PSA: 29.96000
• LogP: 2.61730
• Storage Temp.: 0-10°C
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 280.88739
• Heavy Atom Count: 11
• Complexity: 127

Purity/Quality:

99% ^*data from raw suppliers

3-(Bromoacetyl)pyridine Hydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39-37/39-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CN=C1)C(=O)CBr.Br
• Uses: 3-(2-Bromoacetyl)pyridine hydrobromide is a useful synthetic intermediate

Technology Process of 3-(Bromoacetyl)pyridine hydrobromide

There total 3 articles about 3-(Bromoacetyl)pyridine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl-3-pyridylketone (350-03-8) → 3-(2-bromoacetyl)pyridine hydrobromide (17694-68-7)

Guidance literature:

With hydrogen bromide; bromine; acetic acid; In water; at 40 - 75 ℃; for 4h;

Reference yield:

methyl-3-pyridylketone (350-03-8) + Pyridine hydrobromide (18820-82-1) → 3-(2-bromoacetyl)pyridine hydrobromide (17694-68-7)

Guidance literature:

With bromine;

DOI:10.1002/hc.20308

Reference yield:

→ 3-(2-bromoacetyl)pyridine hydrobromide (17694-68-7)

Guidance literature:

upstream raw materials:

methyl-3-pyridylketone

Pyridine hydrobromide

Downstream raw materials:

(2-piperidin-3-yl-[1,3]dioxolan-2-yl)-methanol

(2-pyridin-3-yl-[1,3]dioxolan-2-yl)-methanol

2-(3-methoxyphenylsulfanyl)-1-pyridin-3-yl ethanone

2-benzoyl-4-oxo-4-pyridin-3-yl-butyronitrile