BMS 303141

Base Information

Chemical Name:BMS 303141
CAS No.:943962-47-8
Molecular Formula:C₁₉H₁₅Cl₂NO₄S
Molecular Weight:424.304
Hs Code.:
Mol file:943962-47-8.mol

Synonyms:3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide;BMS 303141;3,5-dichloro-2-hydroxy-N-(4-methoxybiphenyl-3-yl)benzenesulfonamide;

Suppliers and Price of BMS 303141

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
BMS 303141
10mg
$ 466.00

Usbiological
BMS 303141
10mg
$ 452.00

TRC
BMS-303141
50mg
$ 415.00

Tocris
BMS303141 ≥99%(HPLC)
50
$ 791.00

Tocris
BMS303141 ≥99%(HPLC)
10
$ 197.00

Sigma-Aldrich
BMS-303141 ≥98% (HPLC)
5mg
$ 100.00

Sigma-Aldrich
BMS-303141 ≥98% (HPLC)
25mg
$ 404.00

DC Chemicals
BMS-303141 >98%
1 g
$ 1800.00

DC Chemicals
BMS-303141 >98%
250 mg
$ 900.00

DC Chemicals
BMS-303141 >98%
100 mg
$ 450.00

Total 29 raw suppliers

Chemical Property of BMS 303141

Chemical Property:

Boiling Point:591.5±60.0 °C(Predicted)
PKA:4.94±0.48(Predicted)
PSA：84.01000
Density:1.462±0.06 g/cm3(Predicted)
LogP:6.32920
Storage Temp.:2-8°C
Solubility.:DMSO: soluble20mg/mL, clear

Purity/Quality:

99%, ^*data from raw suppliers

BMS 303141 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description BMS-303141 (943963-47-8) is a potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 μM. Inhibits lipid biosynthesis, IC50=8 μM in HepG2 cells.1,2?Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2?A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2?Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3?Reduces cell cycle progression in iBN cells.4
Uses BMS-303141 has been used for inhibition of ATP citrate lyase in breast cancer cell lines.

Technology Process of BMS 303141

There total 1 articles about BMS 303141 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%