Methyl trans-3-aMinocyclohexanecarboxylate hydrochloride, 97%

Base Information

• Chemical Name: Methyl trans-3-aMinocyclohexanecarboxylate hydrochloride, 97%
• CAS No.: 712313-64-9
• Molecular Formula: C8H15NO2 .ClH
• Molecular Weight: 193.67
• Mol file: 712313-64-9.mol

Synonyms:trans-Methyl-3-aminocyclohexanecarboxylate hydrochloride;Methyltrans-3-aminocyclohexanecarboxylatehydrochloride,97%;Methyl trans-3-aMinocyclohexanecarboxylate hydrochloride, 97%;methyl rel-(1S,3S)-3-aminocyclohexane-1-carboxylate hydrochloride;trans-3-Amino-cyclohexanecarboxylic acid methyl ester hydrochloride

Chemical Property of Methyl trans-3-aMinocyclohexanecarboxylate hydrochloride, 97%

Chemical Property:

• PSA: 52.32000
• LogP: 2.17920
• Water Solubility.: Insoluble in water.

Purity/Quality:

99% ^*data from raw suppliers

trans-Methyl-3-aminocyclohexanecarboxylatehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Methyl trans-3-aminocyclohexanecarboxylate hydrochloride used as catalyst in pharmaceutical research.

Technology Process of Methyl trans-3-aMinocyclohexanecarboxylate hydrochloride, 97%

There total 13 articles about Methyl trans-3-aMinocyclohexanecarboxylate hydrochloride, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(1S,3R)-3-((tert-butoxycarbonyl)amino)cyclo hexane-1-carboxylic acid (222530-34-9,218772-92-0,222530-33-8) + methanol (67-56-1) → (1S,3R)-methyl 3-aminocyclohexanecarboxylate hydrochloride (712313-64-9,87360-22-3)

Guidance literature:

With thionyl chloride; at 20 ℃;

Reference yield: 98.0%

methanol (67-56-1) + C12H21NO4 (218772-92-0,222530-33-8) → C8H15NO2*ClH (712313-64-9,87360-22-3)

Guidance literature:

With thionyl chloride; at 20 ℃; for 2h;

Reference yield: 94.5%

methanol (67-56-1) + cis-3-aminocyclohexanecarboxylic acid (41235-88-5,933445-51-3,933445-54-6) → methyl cis-3-aminocyclohexane-1-carboxylate hydrochloride (712313-64-9,87360-22-3)

Guidance literature:

With thionyl chloride; at 60 ℃; for 20.5h; Sealed tube;

upstream raw materials:

chloro-trimethyl-silane

3-amino-cyclohexanecarboxylic acid ; hydrochloride

3-aminocyclohexanecarboxylic acid

methanol

Refernces

• 1、 -. "3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF". Paragraph 00324. . Retrieved 2017/09/27.
• 2、 -. "INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7)". Paragraph 180; 181. . Retrieved 2016/12/26.