Methyl 3,5-difluoro-4-hydroxybenzoate

Base Information

Chemical Name:Methyl 3,5-difluoro-4-hydroxybenzoate
CAS No.:170572-47-1
Molecular Formula:C8H6F2O3
Molecular Weight:188.1306
Hs Code.:2918290090
DSSTox Substance ID:DTXSID00707108
Nikkaji Number:J1.298.343C
Wikidata:Q82640767
Mol file:170572-47-1.mol

Synonyms:Methyl 3,5-difluoro-4-hydroxybenzoate;170572-47-1;3,5-DIFLUORO-4-HYDROXYBENZOIc acid METHYL ESTER;methyl3,5-difluoro-4-hydroxybenzoate;SCHEMBL198937;Benzoic acid, 3,5-difluoro-4-hydroxy-, methyl ester;DTXSID00707108;GNFQIZAZPRYIFJ-UHFFFAOYSA-N;MFCD12406862;AKOS016012948;MS-9672;CS-0187485;C73278;EN300-3195965;3,5-difluoro-4-hydroxy-benzoic acid methyl ester;A927354;Z1255443616

Suppliers and Price of Methyl 3,5-difluoro-4-hydroxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl3,5-difluoro-4-hydroxybenzoate
50mg
$ 65.00

Crysdot
Methyl3,5-difluoro-4-hydroxybenzoate 97%
1g
$ 142.00

Biosynth Carbosynth
3,5-Difluoro-4-hydroxybenzoic acid methyl ester
1 g
$ 97.50

Biosynth Carbosynth
3,5-Difluoro-4-hydroxybenzoic acid methyl ester
500 mg
$ 60.00

Biosynth Carbosynth
3,5-Difluoro-4-hydroxybenzoic acid methyl ester
5 g
$ 312.50

Biosynth Carbosynth
3,5-Difluoro-4-hydroxybenzoic acid methyl ester
2 g
$ 156.00

Apolloscientific
Methyl3,5-difluoro-4-hydroxybenzoate 98%
1g
$ 150.00

Apolloscientific
Methyl3,5-difluoro-4-hydroxybenzoate 98%
10g
$ 665.00

Apolloscientific
Methyl3,5-difluoro-4-hydroxybenzoate 98%
5g
$ 445.00

AOBChem
Methyl3,5-difluoro-4-hydroxybenzoate 95%
25g
$ 962.00

Total 10 raw suppliers

Chemical Property of Methyl 3,5-difluoro-4-hydroxybenzoate

Chemical Property:

PSA：46.53000
LogP:1.45700
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:188.02850037
Heavy Atom Count:13
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

Methyl3,5-difluoro-4-hydroxybenzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC(=C(C(=C1)F)O)F

Technology Process of Methyl 3,5-difluoro-4-hydroxybenzoate

There total 5 articles about Methyl 3,5-difluoro-4-hydroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1431533-45-7
methyl 4-(benzyloxy)-3,5-difluorobenzoate

: 170572-47-1
methyl 3,5-difluoro-4-hydroxybenzoate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 4h;

Reference yield:

: 67-56-1
methanol

: 935527-22-3
4-(benzyloxy)-3,5-difluorobenzonitrile

: 170572-47-1
methyl 3,5-difluoro-4-hydroxybenzoate

Guidance literature:: With sulfuric acid; for 120h; Heating / reflux;

Reference yield:

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 403-01-0
methyl 3-fluoro-4-hydroxybenzoate

: 170572-47-1
methyl 3,5-difluoro-4-hydroxybenzoate

Guidance literature:: With formic acid; fluorine; at 10 ℃; for 1.75h; Title compound not separated from byproducts;
DOI:10.1016/S0022-1139(99)00238-9