[2-(methylamino)ethyl]phosphonic acid

Base Information

Chemical Name:[2-(methylamino)ethyl]phosphonic acid
CAS No.:14596-55-5
Molecular Formula:C3H10 N O3 P
Molecular Weight:139.0902
Hs Code.:
NSC Number:133872
DSSTox Substance ID:DTXSID20299959
Nikkaji Number:J431.381J
Wikidata:Q27107474
Metabolomics Workbench ID:53311
Mol file:14596-55-5.mol

Synonyms:2-(Methylamino)ethylphosphonicacid; N-Methyl-2-aminoethylphosphonic acid; N-Methylciliatine; N-Monomethylciliatine;NSC 133872

Suppliers and Price of [2-(methylamino)ethyl]phosphonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of [2-(methylamino)ethyl]phosphonic acid

Chemical Property:

Vapor Pressure:6.29E-05mmHg at 25°C
Boiling Point:321.1°Cat760mmHg
Flash Point:148°C
Density:1.311g/cm³
XLogP3:-4.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:139.03983018
Heavy Atom Count:8
Complexity:98.7

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNCCP(=O)(O)O
General Description [2-(Methylamino)ethyl]phosphonic acid (also known as N-Methylciliatine) is an N-substituted derivative of 2-aminoethylphosphonic acid (AEPA), synthesized via a one-step reaction of 2-chloroethylphosphonic acid with methylamine (H₂NMe) in a dilute alkaline solution below 20 °C. The reaction is facilitated by a catalytic amount of potassium iodide (KI), significantly improving yields (78.2–88.0% with KI compared to 35.6–48.6% without). [2-(methylamino)ethyl]phosphonic acid belongs to a class of phosphonic acid derivatives with potential biological relevance, though the abstract does not elaborate on its specific properties or applications.

Technology Process of [2-(methylamino)ethyl]phosphonic acid

There total 6 articles about [2-(methylamino)ethyl]phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%