6-Methoxy-3-phenyl-2-quinolinol

Base Information

Chemical Name:6-Methoxy-3-phenyl-2-quinolinol
CAS No.:256424-26-7
Molecular Formula:C₁₆H₁₃NO₂
Molecular Weight:251.285
Hs Code.:
DSSTox Substance ID:DTXSID50431981
Nikkaji Number:J2.071.628B
Wikidata:Q82246037
Mol file:256424-26-7.mol

Synonyms:6-METHOXY-3-PHENYL-2-QUINOLINOL;256424-26-7;6-METHOXY-3-PHENYLQUINOLIN-2-OL;2-Hydroxy-6-methoxy-3-phenylquinoline;SCHEMBL7196311;DTXSID50431981;MFCD09997960;3-Phenyl-6-methoxy-1,2-dihydroquinoline-2-one

Suppliers and Price of 6-Methoxy-3-phenyl-2-quinolinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-HYDROXY-6-METHOXY-3-PHENYLQUINOLINE 95.00%
5MG
$ 503.11

Total 2 raw suppliers

Chemical Property of 6-Methoxy-3-phenyl-2-quinolinol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:484.653°C at 760 mmHg
Flash Point:246.909°C
PSA：42.35000
Density:1.207g/cm³
LogP:3.61600
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:371

Purity/Quality:

97% ^*data from raw suppliers

2-HYDROXY-6-METHOXY-3-PHENYLQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)NC(=O)C(=C2)C3=CC=CC=C3

Technology Process of 6-Methoxy-3-phenyl-2-quinolinol

There total 2 articles about 6-Methoxy-3-phenyl-2-quinolinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 256424-26-7
6-methoxy-3-phenyl(1H)quinolin-2(1H)-one

Guidance literature:: With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine; molybdenum hexacarbonyl; In 1,2-dimethoxyethane; water; at 100 ℃; for 26h; Sealed tube;

Reference yield:

: 98-86-2
acetophenone

: 3471-32-7
4-Methoxyphenylhydrazine

: 256424-26-7
6-methoxy-3-phenyl(1H)quinolin-2(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: polyphosphoric acid / 0.67 h / 100 - 110 °C

2: polyphosphoric acid / 1.5 h / 80 - 100 °C

With polyphosphoric acid; 1: |Fischer Indole Synthesis;
DOI:10.1039/c4ra14406f