L-alpha-Methyl DOPA Methyl Ester Hydrochloride

Base Information

Chemical Name:L-alpha-Methyl DOPA Methyl Ester Hydrochloride
CAS No.:115054-62-1
Molecular Formula:C11H16ClNO4
Molecular Weight:261.705
Hs Code.:
DSSTox Substance ID:DTXSID10544521
Mol file:115054-62-1.mol

Synonyms:115054-62-1;L-alpha-Methyl DOPA Methyl Ester Hydrochloride;methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate;hydrochloride;L-|A-Methyl DOPA Methyl Ester Hydrochloride;L-a-Methyl DOPA Methyl Ester Hydrochloride;DTXSID10544521;CID 13589971;Methyl 3-hydroxy-alpha-methyl-L-tyrosinate--hydrogen chloride (1/1);METHYL (2S)-2-AMINO-3-(3,4-DIHYDROXYPHENYL)-2-METHYLPROPANOATE HYDROCHLORIDE;Methyl (2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate Hydrochloride (Methyldopa Methyl Ester Hydrochloride);Methyl (2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoate Hydrochloride;Methyldopa Methyl Ester Hydrochloride;L-Tyrosine, 3-hydroxy-alpha-methyl-, methyl ester, hydrochloride (1:1);L-Tyrosine, 3-hydroxy-alpha-methyl-, methyl ester, hydrochloride (9CI);L-alpha-Methyldopa methyl ester hydrochloride;Carbidopa Impurity B as Hydrochloride

Suppliers and Price of L-alpha-Methyl DOPA Methyl Ester Hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
L-α-MethylDOPAMethylEsterHydrochloride
1g
$ 120.00

Total 7 raw suppliers

Chemical Property of L-alpha-Methyl DOPA Methyl Ester Hydrochloride

Chemical Property:

PSA：92.78000
LogP:2.03300
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:261.0767857
Heavy Atom Count:17
Complexity:258

Purity/Quality:

99% ^*data from raw suppliers

L-α-MethylDOPAMethylEsterHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC(=C(C=C1)O)O)(C(=O)OC)N.Cl
Isomeric SMILES:C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)OC)N.Cl
Uses Methyldopa angiotensin II analog.

Technology Process of L-alpha-Methyl DOPA Methyl Ester Hydrochloride

There total 2 articles about L-alpha-Methyl DOPA Methyl Ester Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 67-56-1
methanol

: 555-30-6,555-29-3,88620-56-8
methyldopa

: 115054-62-1
α-methyl-β-3,4-dihydroxyphenyl-(L)-alanine methyl ester hydrochloride

Guidance literature:: With thionyl chloride; at -15 - 20 ℃; for 72h; Heating / reflux;

Reference yield:

: 67-56-1
methanol

: 555-30-6,555-29-3,88620-56-8
3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine

: 6014-29-5,115054-62-1
αMeDopa-OMe*HCl

Guidance literature:: With thionyl chloride; at 60 ℃; for 168h;
DOI:10.1055/s-1991-26380

Reference yield: 67.0%

: 13139-17-8
N-(Benzyloxycarbonyloxy)succinimide

: 115054-62-1
α-methyl-β-3,4-dihydroxyphenyl-(L)-alanine methyl ester hydrochloride

: 1032708-83-0
Z-L-Mdp-OMe

Guidance literature:: α-methyl-β-3,4-dihydroxyphenyl-(L)-alanine methyl ester hydrochloride; With triethylamine; In tetrahydrofuran; acetonitrile; for 0.0833333h; Cooling with ice;

N-(Benzyloxycarbonyloxy)succinimide; In tetrahydrofuran; acetonitrile; at 0 - 20 ℃; for 97h;
DOI:10.1002/ejoc.200700917