6-Bromo-4-nitro-2,2'-bipyridine-1-oxide

Base Information

Chemical Name:6-Bromo-4-nitro-2,2'-bipyridine-1-oxide
CAS No.:205052-97-7
Molecular Formula:C₁₀H₆BrN₃O₃
Molecular Weight:296.08
Hs Code.:
DSSTox Substance ID:DTXSID00443534
Wikidata:Q82261416
Mol file:205052-97-7.mol

Synonyms:6-BROMO-4-NITRO-2,2'-BIPYRIDINE-1-OXIDE;205052-97-7;DTXSID00443534;J-400782

Suppliers and Price of 6-Bromo-4-nitro-2,2'-bipyridine-1-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-BROMO-4-NITRO-2,2'-BIPYRIDINE-1-OXIDE 95.00%
5MG
$ 495.99

Total 1 raw suppliers

Chemical Property of 6-Bromo-4-nitro-2,2'-bipyridine-1-oxide

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:518.783°C at 760 mmHg
Flash Point:267.551°C
PSA：84.17000
Density:1.769g/cm³
LogP:3.37100
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:294.95925
Heavy Atom Count:17
Complexity:287

Purity/Quality:: 6-BROMO-4-NITRO-2,2'-BIPYRIDINE-1-OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=NC(=C1)C2=[N+](C(=CC(=C2)[N+](=O)[O-])Br)[O-]

Technology Process of 6-Bromo-4-nitro-2,2'-bipyridine-1-oxide

There total 4 articles about 6-Bromo-4-nitro-2,2'-bipyridine-1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 205052-95-5
6-bromo-2,2'-bipyridine N-oxide

: 205052-97-7
6-bromo-4-nitro-2,2'-bipyridine N-oxide

Guidance literature:: With sulfuric acid; potassium nitrate; at 80 ℃; for 20h;
DOI:10.1021/jo972022i

Reference yield: 60.0%

: 98027-81-7
2,6-dibromo-4-nitro-pyridine 1-oxide

: 17997-47-6
2-tri-n-butylstannylpyridine

: 205052-97-7
6-bromo-4-nitro-2,2'-bipyridine N-oxide

Guidance literature:: tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; for 16h; Heating;
DOI:10.1002/1099-0690(200105)2001:10<1853::aid-ejoc1853>3.0.co;2-s

Reference yield:

: 366-18-7
[2,2]bipyridinyl

: 205052-97-7
6-bromo-4-nitro-2,2'-bipyridine N-oxide

Guidance literature:: Multi-step reaction with 3 steps

1.1: 79 percent / m-CPBA / CHCl₃ / 13 h / 25 °C

2.1: LDA / hexane; tetrahydrofuran / 0.5 h / -70 °C

2.2: 70 percent / BrCN / hexane; tetrahydrofuran / 0.25 h / -70 °C

3.1: 66 percent / KNO₃; conc. H₂SO₄ / 20 h / 80 °C

With sulfuric acid; potassium nitrate; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; In tetrahydrofuran; hexane; chloroform; 1.1: Oxidation / 2.1: Metallation / 2.2: Bromination / 3.1: Nitration;
DOI:10.1021/jo972022i