Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside

Base Information

Chemical Name:Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside
CAS No.:636581-81-2
Molecular Formula:C20H20Cl4O5
Molecular Weight:482.188
Hs Code.:
Mol file:636581-81-2.mol

Synonyms:Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside

Suppliers and Price of Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(3R,4S,5R)-4-((2,4-Dichlorobenzyl)oxy)-5-(((2,4-dichlorobenzyl)oxy)methyl)-2-methoxytetrahydrofuran-3-ol 97%
1g
$ 1131.00

Total 12 raw suppliers

Chemical Property of Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside

Chemical Property:

PSA：57.15000
LogP:5.13440

Purity/Quality:

97% ^*data from raw suppliers

(3R,4S,5R)-4-((2,4-Dichlorobenzyl)oxy)-5-(((2,4-dichlorobenzyl)oxy)methyl)-2-methoxytetrahydrofuran-3-ol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside

There total 2 articles about Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 677299-16-0
(2R,3R,4R)-3,4-bis((2,4-dichlorobenzyl)oxy)-2-(((2,4-dichlorobenzyl)oxy)methyl)-5-methoxytetrahydrofuran

: 636581-81-2
3,5-bis-O-(2,4-dichlorobenzyl)-1-O-methyl-α-D-ribofuranose

Guidance literature:: (2R,3R,4R)-3,4-bis((2,4-dichlorobenzyl)oxy)-2-(((2,4-dichlorobenzyl)oxy)methyl)-5-methoxytetrahydrofuran; With tin(ll) chloride; In dichloromethane; at 0 - 3 ℃; for 43h;

With water; sodium hydrogencarbonate; In dichloromethane;

Reference yield:

: (3R,4R,5R)-5-(2,4-dichloro-benzyloxymethyl)-4-(2,4-dichlorobenzyloxy)-2-methoxy-tetrahydrofuran-3-yl acetate

: 636581-81-2
3,5-bis-O-(2,4-dichlorobenzyl)-1-O-methyl-α-D-ribofuranose

Guidance literature:: With methanol; sodium methylate; at 20 ℃; for 0.5h; Product distribution / selectivity;

Reference yield:

: 636581-81-2
3,5-bis-O-(2,4-dichlorobenzyl)-1-O-methyl-α-D-ribofuranose

: 1044589-82-3
(2R,3R,4R,5R)-2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Guidance literature:: Multi-step reaction with 6 steps

1.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; trichloroisocyanuric acid / dichloromethane / 20 °C / Cooling with ice

2.1: tetrahydrofuran / 3 h / 0 °C

2.2: Cooling

3.1: hydrogen bromide; acetic acid / dichloromethane / 1.5 h / 20 °C

4.1: sodium hydride / acetonitrile / 0.5 h / 20 °C

4.2: 18 h / 20 °C

5.1: boron trichloride / dichloromethane / -78 °C

5.2: 0.5 h / 0 °C

6.1: ammonia / water / 5 h / 100 °C

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; trichloroisocyanuric acid; ammonia; hydrogen bromide; boron trichloride; sodium hydride; acetic acid; In tetrahydrofuran; dichloromethane; water; acetonitrile;