(Dibromomethyl)trimethylsilane

Base Information

• Chemical Name: (Dibromomethyl)trimethylsilane
• CAS No.: 2612-42-2
• Molecular Formula: C4H10Br2Si
• Molecular Weight: 246.017
• Hs Code.: 2931900090
• Mol file: 2612-42-2.mol

Synonyms:(Dibromomethyl)trimethylsilane;Dibromo(trimethylsilyl)methane

Chemical Property of (Dibromomethyl)trimethylsilane

Chemical Property:

• Boiling Point: 82.5 °C(Press: 50 Torr)
• PSA: 0.00000
• Density: 1.566±0.06 g/cm3(Predicted)
• LogP: 3.39960
• Solubility.: sol most organic solvents.

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Physical properties: bp 49.5–51.5°C/12 mmHg; d 1.519 g cm?3.
• Uses: Reaction of (dibromomethyl)- trimethylsilane with n-butyllithium at ?110°C results in the formation of trimethylsilylbromomethyllithium. The silane and the n-BuLi are added simultaneously in order to suppress side reactions. Treatment of the intermediate lithium reagent with chlorotrimethylsilane (eq 1) or mercury(II) bromide (eq 2) affords bis(trimethylsilyl)bromomethane or bis(trimethylsilylbromomethyl) mercury, respectively. If the lithium reagent is allowed to warm in the presence of cyclohexene, the only reaction observed is an alkylation with the n-butyl bromide formed in the exchange reaction. The alkylated product is formed in 89% yield.

Technology Process of (Dibromomethyl)trimethylsilane

There total 6 articles about (Dibromomethyl)trimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

chloro-trimethyl-silane (75-77-4) + Bromoform (75-25-2) → (dibromomethyl)trimethylsilane (2612-42-2) + Tris(trimethylsilyl)methane (1068-69-5) + bis(trimethylsilyl)methyl bromide (29955-12-2)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; Yields of byproduct given;

Reference yield:

chloro-trimethyl-silane (75-77-4) + dibromomethyl-magnesium chloride (17609-20-0) → (dibromomethyl)trimethylsilane (2612-42-2)

Guidance literature:

In tetrahydrofuran; at -80 ℃;

Reference yield:

chloro-trimethyl-silane (75-77-4) + 1,1-dibromomethane (74-95-3) → (dibromomethyl)trimethylsilane (2612-42-2)

Guidance literature:

Multistep reaction; (i) LDA, (ii) /BRN= 1209232/;

upstream raw materials:

tetramethylsilane

chloro-trimethyl-silane

Bromoform

dibromomethyl-magnesium chloride

Downstream raw materials:

bis(trimethylsilyl)methyl bromide

(bromomethyl)trimethylsilane

(E)-trimethyl(4-phenylbut-1-en-1-yl)silane

1-cyclohexyl-1-(trimethylsilyl)methanol