10-Methyloctadecanoic acid ethyl ester

Base Information

• Chemical Name: 10-Methyloctadecanoic acid ethyl ester
• CAS No.: 55334-35-5
• Molecular Formula: C₂₁H₄₂O₂
• Molecular Weight: 326.563
• Mol file: 55334-35-5.mol

Synonyms:10-Methyloctadecanoic acid ethyl ester;10-Methylstearic acid ethyl ester

Chemical Property of 10-Methyloctadecanoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 10-Methyloctadecanoic acid ethyl ester

There total 34 articles about 10-Methyloctadecanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethyl 6-heptenoate (25118-23-4) + (S)-2,6-dimethyltetradec-2-ene (67214-63-5) → (+)(S)-10-methyl-stearic acid ethyl ester (57289-48-2,55334-35-5)

Guidance literature:

ethyl 6-heptenoate; (S)-2,6-dimethyltetradec-2-ene; With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane;

With hydrogen; In ethyl acetate;

DOI:10.1039/c9sc05248h

Reference yield: 84.0%

10-Methyl-octadecanoic acid (542-47-2,80508-15-2) + ethyl iodide (75-03-6) → ethyl (R,S)-10-methyloctadecanoate (158648-65-8,55334-35-5)

Guidance literature:

With tetra(n-butyl)ammonium hydroxide; In dichloromethane; for 16h;

DOI:10.1016/0009-3084(94)90067-1

Reference yield: 76.0%

(R)-2,6-dimethyl-tetradec-2-ene (113631-39-3) + ethyl 6-heptenoate (25118-23-4) → ethyl (R)-10-methyloctadecanoate (1082670-89-0,55334-35-5)

Guidance literature:

(R)-2,6-dimethyl-tetradec-2-ene; ethyl 6-heptenoate; With Hoveyda-Grubbs catalyst second generation; In dichloromethane; for 24h; Reflux;

With hydrogen; In ethyl acetate; at 20 ℃; under 27752.8 Torr;

DOI:10.1039/c7ob01786c

upstream raw materials:

10-Methyl-octadecanoic acid

ethyl iodide

hydrogenchloride

10-methyl-9-oxo-octadecanoic acid ethyl ester

Downstream raw materials:

(R)-10-methyloctadecanoic acid

(S)-10-methyloctadecanoic acid

Refernces

• 1、 Burugupalli, Satvika,Richardson, Mark B.,Williams, Spencer J.. "Total synthesis and mass spectrometric analysis of a: Mycobacterium tuberculosis phosphatidylglycerol featuring a two-step synthesis of (R)-tuberculostearic acid". . p. 7422 - 7429. Retrieved 2017/09/25.