CHEMBRDG-BB 9033713

Base Information

• Chemical Name: CHEMBRDG-BB 9033713
• CAS No.: 206551-32-8
• Molecular Formula: C9H10BrNO2
• Molecular Weight: 244.088
• Mol file: 206551-32-8.mol

Synonyms:CHEMBRDG-BB 9033713;METHYL 2-AMINO-3-BROMO-5-METHYLBENZOATE

Chemical Property of CHEMBRDG-BB 9033713

Chemical Property:

• Boiling Point: 309.2±37.0 °C(Predicted)
• PSA: 52.32000
• Density: 1.506±0.06 g/cm3(Predicted)
• LogP: 2.70750

Purity/Quality:

2-Amino-3-bromo-5-methyl-benzoicacidmethylester 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHEMBRDG-BB 9033713

There total 6 articles about CHEMBRDG-BB 9033713 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methanol (67-56-1) + 2-amino-3-bromo-5-methylbenzoic acid (13091-43-5) → methyl 2-amino-3-bromo-5-methyl benzoate (206551-32-8)

Guidance literature:

With sulfuric acid; for 15h; Reflux;

Reference yield: 84.0%

2-amino-3-bromo-5-methylbenzoic acid (13091-43-5) → methyl 2-amino-3-bromo-5-methyl benzoate (206551-32-8)

Guidance literature:

With thionyl chloride; In methanol; at 65 ℃; for 192h;

Reference yield:

2-hydroxyimino-N-p-tolyl-acetamide (1132-40-7) → methyl 2-amino-3-bromo-5-methyl benzoate (206551-32-8)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogenchloride / water / 0.5 h / 50 - 80 °C

2: N-Bromosuccinimide / 24 h / 20 °C

3: water; sodium hydroxide; dihydrogen peroxide / 50 °C

4: sulfuric acid / 15 h / Reflux

With hydrogenchloride; N-Bromosuccinimide; sulfuric acid; water; dihydrogen peroxide; sodium hydroxide; In water;

upstream raw materials:

methanol

2-amino-3-bromo-5-methylbenzoic acid

7-bromo-5-methyl-2,3-dihydro-1H-indole-2,3-dione

5-methyl-indole-2,3-dione

Downstream raw materials:

3-Bromo-2-(4-methoxy-benzenesulfonylamino)-5-methyl-benzoic acid methyl ester

C₁₇H₁₇N₅O₂

C₁₀H₉BrN₂O

C₁₁H₁₁N₃O₂