1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-D-erythrohexitol

Base Information

Chemical Name:1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-D-erythrohexitol
CAS No.:603130-12-7
Molecular Formula:C11H21NO4
Molecular Weight:231.292
Hs Code.:
Mol file:603130-12-7.mol

Synonyms:1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-D-erythrohexitol;tert-Butyl (6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)carbamate;tert-butyl N-[(3R,6S)-6-(hydroxymethyl)oxan-3-yl]carbamate

Suppliers and Price of 1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-D-erythrohexitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-D-erythrohexitol
25mg
$ 160.00

TRC
1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-D-erythrohexitol
250mg
$ 1260.00

Crysdot
tert-Butyl((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)carbamate 95+%
1g
$ 1265.00

Chemenu
tert-Butyl((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)carbamate 95%
1g
$ 1192.00

Biosynth Carbosynth
1,5Anhydro-2,3,4-trideoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-D-erythrohexitol
10 mg
$ 80.00

Biosynth Carbosynth
1,5Anhydro-2,3,4-trideoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-D-erythrohexitol
5 mg
$ 50.00

Biosynth Carbosynth
1,5Anhydro-2,3,4-trideoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-D-erythrohexitol
100 mg
$ 400.00

Biosynth Carbosynth
1,5Anhydro-2,3,4-trideoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-D-erythrohexitol
50 mg
$ 250.00

Biosynth Carbosynth
1,5Anhydro-2,3,4-trideoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-D-erythrohexitol
25 mg
$ 150.00

Ambeed
tert-Butyl((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)carbamate 98%
1g
$ 119.00

Total 11 raw suppliers

Chemical Property of 1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-D-erythrohexitol

Chemical Property:

Boiling Point:365.4±35.0 °C(Predicted)
PKA:11.99±0.40(Predicted)
PSA：67.79000
Density:1.11±0.1 g/cm3(Predicted)
LogP:1.44190
Storage Temp.:2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-D-erythrohexitol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-dimethylethoxy)carbonyl]amino]-D-erythrohexitol acts as a reagent in the preparation of topoisomerase inhibitors with potent anti-gram-positive activity. Used in the formation of dipeptide isoteres.

Technology Process of 1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-D-erythrohexitol

There total 9 articles about 1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-D-erythrohexitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 881656-86-6
tert-butyl ((3R,6S)-6-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-yl)carbamate

: 603130-12-7
1,5-anhydro-2-[(tert-butoxycarbonyl)amino]-2,3,4-trideoxy-D-erythro-hexitol

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethyl acetate; for 3h;

Reference yield: 75.0%

: 603130-11-6
(2S,5R)-5-[(tert-butoxycarbonyl)amino]-2-[(tert-butyldimethylsilanyloxy)methyl]-2,5-dihydro-6H-pyran

: 603130-12-7
1,5-anhydro-2-[(tert-butoxycarbonyl)amino]-2,3,4-trideoxy-D-erythro-hexitol

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 16h;
DOI:10.1002/ejoc.200200710

Reference yield:

: 125901-90-8
(2R,3S)-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-ol

: 603130-12-7
1,5-anhydro-2-[(tert-butoxycarbonyl)amino]-2,3,4-trideoxy-D-erythro-hexitol

Guidance literature:: Multi-step reaction with 6 steps

1: 8.3 g / pyridine / 0 °C

2: 76 percent / DBU / CH₂Cl₂ / 1 h / 0 °C

3: 89 percent / K₂CO₃ / 1,2-dichloro-benzene / 5 h / 180 °C

4: KOH / propan-2-ol / 72 h

5: 1.5 g / CH₂Cl₂

6: 75 percent / H₂ / Pd/C / methanol / 16 h

With pyridine; potassium hydroxide; hydrogen; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium on activated charcoal; In methanol; dichloromethane; 1,2-dichloro-benzene; isopropyl alcohol; 3: Overman rearrangement;
DOI:10.1002/ejoc.200200710