1-(2-Methoxy-5-Morpholinophenyl)thiourea

Base Information

Chemical Name:1-(2-Methoxy-5-Morpholinophenyl)thiourea
CAS No.:383870-59-5
Molecular Formula:C12H17N3O2S
Molecular Weight:267.352
Hs Code.:2934999090
Mol file:383870-59-5.mol

Synonyms:1-(2-Methoxy-5-Morpholinophenyl)thiourea;(2-Methoxy-5-morpholin-4-yl-phenyl)-thiourea;Thiourea,N-[2-methoxy-5-(4-morpholinyl)phenyl]-

Suppliers and Price of 1-(2-Methoxy-5-Morpholinophenyl)thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-Methoxy-5-morpholinophenyl)thiourea 97%
1g
$ 645.00

BLDpharm
1-(2-Methoxy-5-morpholinophenyl)thiourea 97%
1g
$ 1063.00

Alichem
1-(2-Methoxy-5-morpholinophenyl)thiourea
1g
$ 530.25

Total 9 raw suppliers

Chemical Property of 1-(2-Methoxy-5-Morpholinophenyl)thiourea

Chemical Property:

Boiling Point:471.4±55.0 °C(Predicted)
PKA:13.15±0.70(Predicted)
PSA：96.38000
Density:1.304±0.06 g/cm3(Predicted)
LogP:2.04600
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Methoxy-5-morpholinophenyl)thiourea 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2-Methoxy-5-Morpholinophenyl)thiourea

There total 6 articles about 1-(2-Methoxy-5-Morpholinophenyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 383870-86-8
1-benzoyl-3-(2-methoxy-5-morpholin-4-yl-phenyl)thiourea

: 383870-59-5
(2-methoxy-5-morpholin-4-yl-phenyl)thiourea

Guidance literature:: With sodium methylate; In methanol; at 0 - 20 ℃; for 4.5h;

Reference yield:

: 104-94-9
4-methoxy-aniline

: 383870-59-5
(2-methoxy-5-morpholin-4-yl-phenyl)thiourea

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydroxide; tetrabutylammomium bromide / 8 h / Heating

1.2: 12 h / 0 - 5 °C

2.1: sulfuric acid / dichloromethane / 1.5 h / 0 - 5 °C

3.1: ammonium chloride; zinc / ethyl acetate; ethanol / 0.5 h / 22 °C / Inert atmosphere

4.1: acetone / 0.5 h / 22 °C / Inert atmosphere

5.1: sodium methylate / methanol / 3 h / 22 °C / Inert atmosphere

5.2: 1 h / 0 - 5 °C

With sulfuric acid; tetrabutylammomium bromide; sodium methylate; ammonium chloride; sodium hydroxide; zinc; In methanol; ethanol; dichloromethane; ethyl acetate; acetone;
DOI:10.1016/j.ejmech.2021.113214

Reference yield:

: 955095-74-6
4-(4-methoxyhenyl)morpholine nitric acid salt

: 383870-59-5
(2-methoxy-5-morpholin-4-yl-phenyl)thiourea

Guidance literature:: Multi-step reaction with 4 steps

1.1: sulfuric acid / dichloromethane / 1.5 h / 0 - 5 °C

2.1: ammonium chloride; zinc / ethyl acetate; ethanol / 0.5 h / 22 °C / Inert atmosphere

3.1: acetone / 0.5 h / 22 °C / Inert atmosphere

4.1: sodium methylate / methanol / 3 h / 22 °C / Inert atmosphere

4.2: 1 h / 0 - 5 °C

With sulfuric acid; sodium methylate; ammonium chloride; zinc; In methanol; ethanol; dichloromethane; ethyl acetate; acetone;
DOI:10.1016/j.ejmech.2021.113214