2-(Pyrrolidin-1-ylmethyl)pyridin-3-ol

Base Information

Chemical Name:2-(Pyrrolidin-1-ylmethyl)pyridin-3-ol
CAS No.:7149-45-3
Molecular Formula:C₁₀H₁₄N₂O
Molecular Weight:178.234
Hs Code.:
European Community (EC) Number:635-822-4
NSC Number:72099
DSSTox Substance ID:DTXSID40290963
Nikkaji Number:J1.205.631A
Wikidata:Q82028780
ChEMBL ID:CHEMBL4287206

Synonyms:2-(pyrrolidin-1-ylmethyl)pyridin-3-ol;7149-45-3;2-(Pyrrolidin-1-Yl-Methyl)Pyridin-3-Ol;CHEMBL4287206;NSC72099;SCHEMBL9734270;DTXSID40290963;2-(pyrrolidinylmethyl)-3-pyridinol;BDBM50465496;NSC 72099;NSC-72099;AKOS006273750;2-(1-Pyrrolidinylmethyl)pyridine-3-ol;FT-0728725;3-HYDROXY-2-(PYRROLIDINOMETHYL)-PYRIDINE

Suppliers and Price of 2-(Pyrrolidin-1-ylmethyl)pyridin-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-(Pyrrolidin-1-ylmethyl)pyridin-3-ol

Chemical Property:

Vapor Pressure:2.5E-05mmHg at 25°C
Boiling Point:348.4°Cat760mmHg
Flash Point:164.5°C
Density:1.19g/cm³
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:178.110613074
Heavy Atom Count:13
Complexity:157

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CCN(C1)CC2=C(C=CC=N2)O

Technology Process of 2-(Pyrrolidin-1-ylmethyl)pyridin-3-ol

There total 2 articles about 2-(Pyrrolidin-1-ylmethyl)pyridin-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 123-75-1
pyrrolidine

: 109-00-2
3-HYDROXYPYRIDINE

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 7149-45-3
2-(pyrrolidin-1-ylmethyl)pyridin-3-ol

Guidance literature:: In water; for 4h; Reflux;
DOI:10.1021/acs.jmedchem.7b01620

Reference yield: 88.0%

: 7149-45-3
2-(pyrrolidin-1-ylmethyl)pyridin-3-ol

Guidance literature:: In water; for 4h; Reflux;

Reference yield:

: 7149-45-3
2-(pyrrolidin-1-ylmethyl)pyridin-3-ol

: 125130-49-6,137734-83-9,137734-84-0,138154-87-7,138154-88-8
cis-1-<(3,4-dichlorophenyl)acetyl>-3-hydroxy-2-(1-pyrrolidinylmethyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 28 percent / H₂, CH₃CO₂H / PtO₂ / 44 h / 3620.04 Torr / Ambient temperature

2: 1.) 1,1'-carbonyldiimidazole / 1.) THF, RT, 20 min, 2.) THF, RT, 16 h

With hydrogen; acetic acid; 1,1'-carbonyldiimidazole; platinum(IV) oxide;
DOI:10.1021/jm00081a009