benzyl N-(3-oxobutan-2-yl)carbamate

Base Information

Chemical Name:benzyl N-(3-oxobutan-2-yl)carbamate
CAS No.:152169-60-3
Molecular Formula:C12H15NO3
Molecular Weight:266.297
Hs Code.:
DSSTox Substance ID:DTXSID60595841
Mol file:152169-60-3.mol

Synonyms:benzyl N-(3-oxobutan-2-yl)carbamate;1330755-48-0;(1-Methyl-2-oxo-propyl)-carbamic acid benzyl ester;DTXSID60595841;Benzyl (3-oxobutan-2-yl)carbamate;AB61361;CS-0261730;EN300-797276;(1-Methyl-2-oxo-propyl)-carbamicacidbenzylester;Z2049743343

Suppliers and Price of benzyl N-(3-oxobutan-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
BenzylN-[(1R)-1-[Methoxy(methyl)carbamoyl]ethyl]carbamate
500mg
$ 75.00

ChemScene
BenzylN-[(1R)-1-[methoxy(methyl)carbamoyl]ethyl]carbamate
1g
$ 75.00

ChemScene
BenzylN-[(1R)-1-[methoxy(methyl)carbamoyl]ethyl]carbamate
5g
$ 225.00

American Custom Chemicals Corporation
BENZYL N-[(1R)-1-[METHOXY(METHYL)CARBAMOYL]ETHYL]CARBAMATE 95.00%
5MG
$ 456.67

Total 8 raw suppliers

Chemical Property of benzyl N-(3-oxobutan-2-yl)carbamate

Chemical Property:

PSA：67.87000
LogP:1.71200
Solubility.:Chloroform; DMSO
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:221.10519334
Heavy Atom Count:16
Complexity:247

Purity/Quality:

98%,99%, ^*data from raw suppliers

BenzylN-[(1R)-1-[Methoxy(methyl)carbamoyl]ethyl]carbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)C)NC(=O)OCC1=CC=CC=C1
Uses Benzyl N-[(1R)-1-[Methoxy(methyl)carbamoyl]ethyl]carbamate is an intermediate in the synthesis of (R)-1,1-Diethoxy-2-propanamine (D442115), which can be used for the synthesis of N-protected α-amino aldehydes occur as C-terminal units of peptide aldehydes with enzyme inhibitor activity, such as Leupeptin. They can also be used for the preparation of amino sugars, and unusual amino acids.

Technology Process of benzyl N-(3-oxobutan-2-yl)carbamate

There total 4 articles about benzyl N-(3-oxobutan-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 26607-51-2
N-benzyloxycarbonyl-D-alanine

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 152169-60-3,688763-83-9
benzyl {(2R)-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 20h;
DOI:10.1021/ol201828u

Reference yield:

: 26607-51-2
N-benzyloxycarbonyl-D-alanine

: 152169-60-3,688763-83-9
benzyl {(2R)-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: N-methylmorpholine / CH₂Cl₂ / 0.25 h / 0 °C

2: CH₂Cl₂ / 3 h / Ambient temperature

With 4-methyl-morpholine; In dichloromethane;
DOI:10.1021/jm960083n