2-(2-METHOXYBENZOYL)PYRIDINE

Base Information

• Chemical Name: 2-(2-METHOXYBENZOYL)PYRIDINE
• CAS No.: 22945-63-7
• Molecular Formula: C13H11NO2
• Molecular Weight: 213.236
• Hs Code.: 2933399090
• Mol file: 22945-63-7.mol

Synonyms:2-(2-METHOXYBENZOYL)PYRIDINE

Chemical Property of 2-(2-METHOXYBENZOYL)PYRIDINE

Chemical Property:

• Vapor Pressure: 2.24E-06mmHg at 25°C
• Boiling Point: 392.8°C at 760 mmHg
• Flash Point: 191.3°C
• PSA: 39.19000
• Density: 1.154g/cm³
• LogP: 2.32120

Purity/Quality:

97% ^*data from raw suppliers

2-(2-methoxybenzoyl)pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-METHOXYBENZOYL)PYRIDINE

There total 8 articles about 2-(2-METHOXYBENZOYL)PYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2-[(2-methoxyphenyl)methyl]pyridine (35854-43-4) → (2-Methoxyphenyl)(pyridine-2-yl)methanone (22945-63-7)

Guidance literature:

With iron(II) chloride tetrahydrate; oxygen; acetic acid; In dimethyl sulfoxide; at 100 ℃; for 24h;

DOI:10.1002/anie.201108540

Reference yield: 65.0%

2-bromo-pyridine (109-04-6) + 2-methoxybenzoic acid methyl ester (606-45-1) → (2-Methoxyphenyl)(pyridine-2-yl)methanone (22945-63-7)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at 10 ℃; Flow reactor;

DOI:10.1021/op300205j

Reference yield: 58.0%

methanol (67-56-1) + phenyl(pyridin-2-yl)methanone (91-02-1) → (2-Methoxyphenyl)(pyridine-2-yl)methanone (22945-63-7)

Guidance literature:

With dipotassium peroxodisulfate; palladium diacetate; trifluoroacetic acid; at 80 ℃; for 24h; regioselective reaction;

DOI:10.1039/c5ob01500f

upstream raw materials:

2-Cyanopyridine

2-bromoanisole

α-picoline

2,4-dimethyl-3-(pyridin-2-ylmethyl)pentan-3-ol

Downstream raw materials:

(R)-(2-methoxyphenyl)(pyridin-2-yl)methanol

2-hydroxyphenyl radical

Refernces

• 1、 -. "COMPOUNDS FOR AND METHODS OF TREATING DISEASES". Page/Page column 40; 42; 43. . Retrieved 2020/10/09.
• 2、 Karthikeyan,Alamsetti,Sekar. "Isolation and characterization of a trinuclear cobalt complex containing trigonal-prismatic cobalt in secondary alcohol aerobic oxidation". . p. 1665 - 1671. Retrieved 2014/05/06.