2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylicacid

Base Information

Chemical Name:2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylicacid
CAS No.:857200-26-1
Molecular Formula:C12H11N3O2S
Molecular Weight:261.304
Hs Code.:
Mol file:857200-26-1.mol

Synonyms:2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylicacid;2-(methylthio)-4-(phenylamino)-5-pyrimidinecarboxylic acid

Suppliers and Price of 2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylicacid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Anilino-2-(methylthio)pyrimidine-5-carboxylicAcid
50mg
$ 70.00

Crysdot
4-Anilino-2-(methylthio)pyrimidine-5-carboxylicacid 95+%
5g
$ 790.00

Chemenu
4-Anilino-2-(methylthio)pyrimidine-5-carboxylicacid 95%
5g
$ 746.00

Total 1 raw suppliers

Chemical Property of 2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylicacid

Chemical Property:

PSA：100.41000
LogP:2.71330

Purity/Quality:: 4-Anilino-2-(methylthio)pyrimidine-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylicacid

There total 5 articles about 2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 106475-47-2
2-methanesulfanyl-4-phenylamino-pyrimidine-5-carboxylic acid ethyl ester

: 857200-26-1
2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylic acid

Guidance literature:: 2-methanesulfanyl-4-phenylamino-pyrimidine-5-carboxylic acid ethyl ester; With water; sodium hydroxide; In ethanol; at 20 ℃;

With hydrogenchloride; In water;

Reference yield: 74.0%

: 74840-34-9
4-chloro-2-(methylsulfanyl)pyrimidine-5-carboxylic acid

: 62-53-3
aniline

: 857200-26-1
2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylic acid

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 95 ℃; for 16h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.1c00845

Reference yield:

: 62-53-3
aniline

: 857200-26-1
2-(methylthio)-4-(phenylamino)pyrimidine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 20 °C

2: sodium hydroxide; water / ethanol / 20 °C

With water; triethylamine; sodium hydroxide; In tetrahydrofuran; ethanol;