6-Ethylpicolinonitrile

Base Information

Chemical Name:6-Ethylpicolinonitrile
CAS No.:59146-66-6
Molecular Formula:C8H8N2
Molecular Weight:132.16252
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80513840
Wikidata:Q82373845
Mol file:59146-66-6.mol

Synonyms:6-Ethylpicolinonitrile;59146-66-6;6-ethylpyridine-2-carbonitrile;2-Cyano-6-ethylpyridine;SCHEMBL2954219;DTXSID80513840;WVFOQWQNCDNIEI-UHFFFAOYSA-N;MFCD21604038;AKOS015992158;SB11283;CS-0054022;A869262;12Z-5017

Suppliers and Price of 6-Ethylpicolinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
6-Ethylpicolinonitrile
1g
$ 1498.00

Alichem
6-Ethylpicolinonitrile
10g
$ 2083.95

Alichem
6-Ethylpicolinonitrile
25g
$ 4065.41

Alichem
6-Ethylpicolinonitrile
5g
$ 1421.28

Chemenu
6-Ethylpicolinonitrile 95%
5g
$ 1169.00

Chemenu
6-Ethylpicolinonitrile 95%
1g
$ 526.00

Chemenu
6-Ethylpicolinonitrile 95%
10g
$ 1870.00

Matrix Scientific
6-Ethylpicolinonitrile 95+%
1g
$ 1073.00

SynQuest Laboratories
6-Ethylpyridine-2-carbonitrile 97%
1 g
$ 1520.00

Total 13 raw suppliers

Chemical Property of 6-Ethylpicolinonitrile

Chemical Property:

Boiling Point:233.0±20.0 °C(Predicted)
PKA:0.35±0.10(Predicted)
PSA：36.68000
Density:1.05±0.1 g/cm3(Predicted)
LogP:1.51568
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:132.068748264
Heavy Atom Count:10
Complexity:145

Purity/Quality:

97% ^*data from raw suppliers

6-Ethylpicolinonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=NC(=CC=C1)C#N

Technology Process of 6-Ethylpicolinonitrile

There total 5 articles about 6-Ethylpicolinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 4833-24-3
2-ethylpyridine 1-oxide

: 7677-24-9
trimethylsilyl cyanide

: 59146-66-6
6-ethyl-2-cyanopyridine

Guidance literature:: With N,N-Dimethylcarbamoyl chloride; In Nitroethane; at 20 ℃; for 72h;

Reference yield:

: 100-71-0
2-Ethylpyridine

: 59146-66-6
6-ethyl-2-cyanopyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 12 h / 0 - 20 °C

2: N,N-diethylcarbamyl chloride / dichloromethane / 24 h / 20 °C

With N,N-diethylcarbamyl chloride; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1021/jacs.9b13117

Reference yield:

: 21717-29-3
2-amino-6-ethylpyridine

: 59146-66-6
6-ethyl-2-cyanopyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 21 g / aq. hydrobromic acid, Br₂, aq. sodium nitrite / 0.5 h / below 0 deg C

2: 11 g

With hydrogen bromide; bromine; sodium nitrite;