2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid

Base Information

• Chemical Name: 2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid
• CAS No.: 2216-99-1
• Molecular Formula: C11H12O4
• Molecular Weight: 208.214
• Hs Code.: 2918990090
• Mol file: 2216-99-1.mol

Synonyms:2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid;5-Allyl-2-hydroxy-3-Methoxybenzoic acid

Chemical Property of 2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid

Chemical Property:

• PSA: 66.76000
• LogP: 1.82750

Purity/Quality:

5-Allyl-2-hydroxy-3-methoxybenzoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid

There total 8 articles about 2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-hydroxy-3-methoxy-5-(2-propeny)benzoic acid, methyl ester (85614-43-3) → 5-allyl-2-hydroxy-3-methoxybenzoic acid (2216-99-1)

Guidance literature:

2-hydroxy-3-methoxy-5-(2-propeny)benzoic acid, methyl ester; With sodium hydroxide; In water; for 2 - 3h; Reflux;

With hydrogenchloride; In water; Time;

Reference yield:

2-(allyloxy)-3-methoxybenzoic acid (96619-88-4) → 6-allylguaicol (579-60-2) + 5-allyl-2-hydroxy-3-methoxybenzoic acid (2216-99-1)

Guidance literature:

at 250 ℃;

Reference yield:

4-allylguaiacol (97-53-0) + potassium hydrogencarbonate (298-14-6) → 5-allyl-2-hydroxy-3-methoxybenzoic acid (2216-99-1)

Guidance literature:

With 2,3-dihydroxybenzoate decarboxylase from Aspergillus oryzae; In aq. phosphate buffer; at 175 ℃; for 24h; under 11251.1 Torr; regioselective reaction; Autoclave; Enzymatic reaction;

DOI:10.1039/c3ra47719c

upstream raw materials:

2-hydroxy-3-methoxy-5-(2-propeny)benzoic acid, methyl ester

2-(allyloxy)-3-methoxybenzoic acid

4-allylguaiacol

carbon dioxide

Downstream raw materials:

4-allylguaiacol

carbon dioxide

(E)-2-hydroxy-3-methoxy-5-(prop-1-enyl)benzoic acid

2-hydroxy-3-methoxy-5-propylbenzoic acid

Refernces

• 1、 -. "DYE COMPOUND AND COLORED CURABLE RESIN COMPOSITION". Paragraph 0359-0360. . Retrieved 2016/11/17.