(2S,3aS,7aS)-2-[diphenyl[(triMethylsilyl)oxy]Methyl]octahydro-1H-Indole

Base Information

Chemical Name:(2S,3aS,7aS)-2-[diphenyl[(triMethylsilyl)oxy]Methyl]octahydro-1H-Indole
CAS No.:1213770-27-4
Molecular Formula:C24H33NOSi
Molecular Weight:379.618
Hs Code.:
Mol file:1213770-27-4.mol

Synonyms:(2S,3aS,7aS)-2-[diphenyl[(triMethylsilyl)oxy]Methyl]octahydro-1H-Indole

Suppliers and Price of (2S,3aS,7aS)-2-[diphenyl[(triMethylsilyl)oxy]Methyl]octahydro-1H-Indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (2S,3aS,7aS)-2-[diphenyl[(triMethylsilyl)oxy]Methyl]octahydro-1H-Indole

Chemical Property:

PSA：21.26000
LogP:6.03120

Purity/Quality:: >95%,>98%e.e. ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (2S,3aS,7aS)-2-[diphenyl[(triMethylsilyl)oxy]Methyl]octahydro-1H-Indole

There total 5 articles about (2S,3aS,7aS)-2-[diphenyl[(triMethylsilyl)oxy]Methyl]octahydro-1H-Indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 27607-77-8
trimethylsilyl trifluoromethanesulfonate

: 142138-83-8
((2S,3aS,7aS)-octahydro-1H-indol-2-yl)diphenylmethanol

: 1213770-27-4
(2S,3aS,7aS)-2-(diphenyl(trimethylsilyloxy)methyl)octahydro-1H-indole

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1080/00397911.2020.1778034

Reference yield: 84.0%

: 75-77-4
chloro-trimethyl-silane

: 142138-83-8
((2S,3aS,7aS)-octahydro-1H-indol-2-yl)diphenylmethanol

: 1213770-27-4
(2S,3aS,7aS)-2-(diphenyl(trimethylsilyloxy)methyl)octahydro-1H-indole

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/adsc.200900355

Reference yield:

: 80875-98-5,2055118-14-2
(2S,3aS,7aS)-perhydroindole-2-carboxylic acid

: 1213770-27-4
(2S,3aS,7aS)-2-(diphenyl(trimethylsilyloxy)methyl)octahydro-1H-indole

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / 48 h / 20 °C / Inert atmosphere

2: diethyl ether / 0 °C / Inert atmosphere; Reflux

3: potassium hydroxide / methanol / Reflux; Inert atmosphere

4: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

With potassium carbonate; triethylamine; potassium hydroxide; In methanol; diethyl ether; dichloromethane;
DOI:10.1080/00397911.2020.1778034