2,6-Pyridinediacetic acid

Base Information

• Chemical Name: 2,6-Pyridinediacetic acid
• CAS No.: 209215-55-4
• Molecular Formula: C₉H₉NO₄
• Molecular Weight: 195.175
• Mol file: 209215-55-4.mol

Synonyms:2,6-Pyridinediacetic acid

Chemical Property of 2,6-Pyridinediacetic acid

Chemical Property:

• PSA: 87.49000
• LogP: 0.33580

Purity/Quality:

≥95% ^*data from raw suppliers

2,6-PYRIDINEDIACETIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-Pyridinediacetic acid

There total 6 articles about 2,6-Pyridinediacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(6-cyanomethylpyridin-2-yl)acetonitrile (46133-38-4) → 6-bromomethylpyridine-2-carboxylic acid ethylester (209215-55-4)

Guidance literature:

With hydrogenchloride; for 24h; Heating;

Reference yield:

(6-cyanomethylpyridin-2-yl)acetonitrile (46133-38-4) + pyrographite (7440-44-0) → 6-bromomethylpyridine-2-carboxylic acid ethylester (209215-55-4)

Guidance literature:

In hydrogenchloride; water;

Reference yield:

2.6-bis(hydroxymethyl)pyridine (1195-59-1) → 6-bromomethylpyridine-2-carboxylic acid ethylester (209215-55-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / 48percent HBr / 36 h / Heating

2: 56 percent / H₂O / 5 h / 80 - 90 °C

3: 73 percent / conc. HCl / 24 h / Heating

With hydrogenchloride; hydrogen bromide; In water;

upstream raw materials:

2,6-bis-phenylcarbamoylmethyl-pyridine

(6-cyanomethylpyridin-2-yl)acetonitrile

2.6-bis(hydroxymethyl)pyridine

2,6-bis-(bromomethyl)pyridine hydrobromide

Downstream raw materials:

(6-cyanomethylpyridin-2-yl)acetonitrile

(R)-1-[[6-[2-[(R)-2-benzyloxycarbonyl-pyrrolidin-1-yl]-2-oxo-ethyl]-pyridin-2-yl]-acetyl]-pyrrolidine-2-carboxylic acid benzyl ester

Refernces

• 1、 -. "D-proline derivatives". . . Retrieved 2008/06/13.