3'-Trifluoromethoxy-biphenyl-4-carbaldehyde

Base Information

Chemical Name:3'-Trifluoromethoxy-biphenyl-4-carbaldehyde
CAS No.:473257-33-9
Molecular Formula:C14H9F3O2
Molecular Weight:266.2152696
Hs Code.:
DSSTox Substance ID:DTXSID20695255
Wikidata:Q82624385
Mol file:473257-33-9.mol

Synonyms:3'-TRIFLUOROMETHOXY-BIPHENYL-4-CARBALDEHYDE;473257-33-9;4-[3-(trifluoromethoxy)phenyl]benzaldehyde;SCHEMBL505254;DTXSID20695255;AKOS012213788;3'-trifluoromethoxybiphenyl-4-carbaldehyde;A1-14551;3'-(Trifluoromethoxy)[1,1'-biphenyl]-4-carbaldehyde

Suppliers and Price of 3'-Trifluoromethoxy-biphenyl-4-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3'-Trifluoromethoxybiphenyl-4-carbaldehyde 95%
2.500g
$ 1733.00

A1 Biochem Labs
3'-Trifluoromethoxy-biphenyl-4-carbaldehyde 95%
2.5 g
$ 1050.00

Total 2 raw suppliers

Chemical Property of 3'-Trifluoromethoxy-biphenyl-4-carbaldehyde

Chemical Property:

PSA：26.30000
LogP:4.06470
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:266.05546401
Heavy Atom Count:19
Complexity:296

Purity/Quality:

95% ^*data from raw suppliers

3'-Trifluoromethoxybiphenyl-4-carbaldehyde 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OC(F)(F)F)C2=CC=C(C=C2)C=O

Technology Process of 3'-Trifluoromethoxy-biphenyl-4-carbaldehyde

There total 3 articles about 3'-Trifluoromethoxy-biphenyl-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1122-91-4
4-bromo-benzaldehyde

: 179113-90-7
(3-(trifluoromethoxy)phenyl)boronic acid

: 473257-33-9
3'-(trifluoromethoxy)-[1,1'-biphenyl]-4-carbaldehyde

Guidance literature:: 4-bromo-benzaldehyde; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; water; at 20 ℃; for 0.0833333h;

(3-(trifluoromethoxy)phenyl)boronic acid; In tetrahydrofuran; water; at 80 ℃; for 18h;
DOI:10.1021/acs.jmedchem.0c01372

Reference yield: 26.0%

: 473257-33-9
3'-(trifluoromethoxy)-[1,1'-biphenyl]-4-carbaldehyde

Guidance literature:

Reference yield:

: 87199-17-5
4-formylphenylboronic acid,

: 198206-33-6
1-iodo-3-(trifluoromethoxy)benzene

: 473257-33-9
3'-(trifluoromethoxy)-[1,1'-biphenyl]-4-carbaldehyde

Guidance literature:: With potassium carbonate; In ethanol; water; at 80 ℃; for 2.5h; Catalytic behavior; Inert atmosphere;
DOI:10.1002/cctc.201902099