1-(2-Fluoroethoxy)-2-nitrobenzene

Base Information

Chemical Name:1-(2-Fluoroethoxy)-2-nitrobenzene
CAS No.:132838-18-7
Molecular Formula:C8H8FNO3
Molecular Weight:185.1524232
Hs Code.:2909309090
DSSTox Substance ID:DTXSID60567664
Wikidata:Q82453630
Mol file:132838-18-7.mol

Synonyms:1-(2-Fluoroethoxy)-2-nitrobenzene;132838-18-7;DTXSID60567664;MFCD22375007;Benzene, 1-(2-fluoroethoxy)-2-nitro-;BS-20674;CS-0212197

Suppliers and Price of 1-(2-Fluoroethoxy)-2-nitrobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(2-Fluoroethoxy)-2-nitrobenzene
100mg
$ 45.00

Crysdot
1-(2-Fluoroethoxy)-2-nitrobenzene 95+%
25g
$ 452.00

Apolloscientific
1-(2-Fluoroethoxy)-2-nitrobenzene 98%
5g
$ 225.00

Apolloscientific
1-(2-Fluoroethoxy)-2-nitrobenzene 98%
1g
$ 100.00

Apolloscientific
1-(2-Fluoroethoxy)-2-nitrobenzene 98%
25g
$ 595.00

AK Scientific
1-(2-Fluoroethoxy)-2-nitrobenzene
25g
$ 691.00

AK Scientific
1-(2-Fluoroethoxy)-2-nitrobenzene
5g
$ 291.00

Total 4 raw suppliers

Chemical Property of 1-(2-Fluoroethoxy)-2-nitrobenzene

Chemical Property:

Boiling Point:292.1±20.0 °C(Predicted)
PSA：55.05000
Density:1.257±0.06 g/cm3(Predicted)
LogP:2.46630
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:185.04882128
Heavy Atom Count:13
Complexity:171

Purity/Quality:

98%min ^*data from raw suppliers

1-(2-Fluoroethoxy)-2-nitrobenzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)[N+](=O)[O-])OCCF

Technology Process of 1-(2-Fluoroethoxy)-2-nitrobenzene

There total 1 articles about 1-(2-Fluoroethoxy)-2-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 762-49-2
2-fluoroethyl bromide

: 88-75-5,78813-12-4
2-hydroxynitrobenzene

: 132838-18-7
1-(2-fluoroethoxy)-2-nitrobenzene

Guidance literature:: With potassium carbonate; In acetone; for 48h; Reflux;
DOI:10.1002/jlcr.1901

Reference yield:

: 132838-18-7
1-(2-fluoroethoxy)-2-nitrobenzene

: 1547-11-1
2-(2-fluoroethoxy)aniline

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 0 ℃; for 4h; under 750.075 Torr;
DOI:10.1002/jlcr.1901

Reference yield:

: 132838-18-7
1-(2-fluoroethoxy)-2-nitrobenzene

: 1335465-70-7
ethyl 4,6-dichloro-3-((3-(2-(2-fluoroethoxy)phenyl)-1-(2-methoxy-2-oxoethyl)ureido)methyl)-indole-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 0 °C / 750.08 Torr

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 °C / Inert atmosphere

3: dichloromethane / 0 - 20 °C / Inert atmosphere

With palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane;
DOI:10.1002/jlcr.1901