1-ethylphenoxathiin 10,10-dioxide

Base Information

• Chemical Name: 1-ethylphenoxathiin 10,10-dioxide
• CAS No.: 134476-36-1
• Molecular Formula: C₁₄H₁₂O₃S
• Molecular Weight: 260.313
• Mol file: 134476-36-1.mol

Synonyms:BW 1370U87

Chemical Property of 1-ethylphenoxathiin 10,10-dioxide

Chemical Property:

• Vapor Pressure: 1.61E-07mmHg at 25°C
• Boiling Point: 439.7°Cat760mmHg
• Flash Point: 219.7°C
• PSA: 51.75000
• Density: 1.324g/cm³
• LogP: 4.26830

Purity/Quality:

1-ETHYLPHENOXATHIIN 10,10-DIOXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-ethylphenoxathiin 10,10-dioxide

There total 10 articles about 1-ethylphenoxathiin 10,10-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

palladium dihydroxide + 1-(1-Hydroxyethyl)-phenoxathiin-10,10-dioxide (135865-59-7,143285-17-0,143285-18-1) → 1-Ethylphenoxathiin 10,10-dioxide (134476-36-1)

Guidance literature:

With nitrogen; hydrogen; In aqueous perchloric acid; water; acetic acid;

Reference yield:

1-lithiophenoxathiin 10,10-dioxide + phenoxathiin S,S-dioxide (950-47-0) + ethyl iodide (75-03-6) → 1-Ethylphenoxathiin 10,10-dioxide (134476-36-1)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane;

Reference yield:

1-(1-Hydroxyethyl)-phenoxathiin-10,10-dioxide (135865-59-7,143285-17-0,143285-18-1) → 1-Ethylphenoxathiin 10,10-dioxide (134476-36-1)

Guidance literature:

With palladium hydroxide - carbon; hydrogen;

DOI:10.1021/jm00113a039

upstream raw materials:

phenoxathiin S,S-dioxide

ethyl iodide

1-(1-Hydroxyethyl)-phenoxathiin-10,10-dioxide

ortho-mercaptophenol

Refernces

• 1、 Harfenist, Morton,McGee, Daniel P.C.,Reeves, Mark D.,White, Helen L.. "Selective inhibitors of monoamine oxidase (MAO). 5.1,2 1-Substituted phenoxathiin inhibitors containing no nitrogen that inhibit MAO a by binding it to a hydrophobic site". . p. 2118 - 2125. Retrieved 2007/10/03.