950-47-0

Basic information

• Product Name: Phenoxathiin 10,10-dioxide
• Synonyms: Phenoxathiin 10,10-dioxide;Phenoxathiine 10,10-dioxide
• CAS NO: 950-47-0
• Molecular Formula: C₁₂H₈O₃S
• Molecular Weight: 232.2551
• Mol File: 950-47-0.mol

Chemical Properties

• Boiling Point: 413.4°Cat760mmHg
• Flash Point: 203.8°C
• Appearance: /
• Density: 1.418g/cm³
• Vapor Pressure: 1.15E-06mmHg at 25°C
• Refractive Index: 1.653
• CAS DataBase Reference: Phenoxathiin 10,10-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: Phenoxathiin 10,10-dioxide(950-47-0)
• EPA Substance Registry System: Phenoxathiin 10,10-dioxide(950-47-0)

Safety Data

• Hazardous Substances Data: 950-47-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Phenoxathiin 10,10-dioxide is used as a pharmaceutical candidate for its anti-inflammatory and antifungal properties, making it suitable for the development of drugs targeting various inflammatory and fungal infections.
Used in Organic Electronics:
Phenoxathiin 10,10-dioxide is used as a building block in the synthesis of materials for organic electronics due to its strong electronic properties, which can enhance the performance of electronic devices.
Used in Materials Science:
Phenoxathiin 10,10-dioxide is used as a component in the development of new materials with unique properties, leveraging its strong electronic properties and unique structure to create innovative materials for various applications.

InChI:InChI=1/C12H8O3S/c13-16(14)11-7-3-1-5-9(11)15-10-6-2-4-8-12(10)16/h1-8H

Upstream product

• 262-20-4 phenoxathiine 
• 577-19-5 2-nitrophenyl bromide 
• 262-24-8 phenoxatellurine 
• 20912-11-2 2-((2-nitrophenyl)thio)phenol 
• 1121-24-0 ortho-mercaptophenol 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 

Downstream Products

• 105583-03-7 2-nitro-phenoxathiine-10,10-dioxide 
• 14909-73-0 2-Hydroxy-2'-methoxy-diphenylsulfon 
• 14909-74-1 2-Hydroxy-2'-ethoxy-diphenylsulfon 
• 14909-76-3 2-Hydroxy-2'-isopropoxy-diphenylsulfon 
• 15038-67-2 2,2'-dihydroxydiphenyl sulfone 
• 134476-36-1 1-Ethylphenoxathiin 10,10-dioxide 
• 120547-00-4 1-((N-(benzyloxycarbonyl)-L-alanyl)oxy)-9-((methoxycarbonyl)dithio)phenoxathiin 10-oxide 
• 120546-99-8 1-((N-(benzyloxycarbonyl)-L-alanyl)oxy)-9-((methoxycarbonyl)dithio)phenoxathiin 
• 135865-60-0 1-(1,2-Dihydroxyethyl)-phenoxathiin-10,10-dioxide 

Relevant articles and documents

(n5-Cyclo-penta-dienyl)(n6-phenoxathiin 10,10-dioxide)iron(II) hexa-fluoridophosphate and phenoxathiin 10,10-di-oxide

In the structure of the title complex salt, [Fe(C5H 5)(C12H8O3S)]PF6, the coordinated cyclo-penta-dienyl (Cp) and benzene ring planes are almost parallel, with a hinge angle between the planes of 0.8 (2)°. The hinge angle between the planes of the peripheral (coordinated and uncoordinated) benzene rings in the coordinated phenoxathiin 10,10-dioxide mol-ecule is 169.9 (2)°, and the FeCp moiety is located inside the shallow fold of the heterocycle. The hinge angle between the benzene ring planes in the free heterocycle, C 12H8O3S, is 171.49 (6)°.

Selectivity switch in the aerobic oxygenation of sulfides photocatalysed by visible-light-responsive decavanadate

Nanometre-sized metal oxides are promising species for the development of visible-light-responsive photocatalysts for the selective transformation of organic functional groups. In this article, we report that decavanadate ([V10O28]6-, V10) behaved as an efficient visible-light-responsive photocatalyst in the product-selective oxygenation of sulfides achieved using O2 (1 atm) as the green oxidant. In particular, we revealed that visible-light-responsive photocatalysis of V10 showed remarkable activity for the oxygenation of structurally diverse sulfides to form the corresponding sulfones using O2 in methyl ethyl ketone (MEK). Furthermore, by simply adding water to the reaction mixture, the product selectivity of sulfide oxygenation can be significantly switched toward the production of sulfoxides, without concomitant loss of photocatalytic activity. Based on experimental evidence, we inferred the following mechanistic steps for this photocatalytic system: the aerobic oxygenation of sulfides to form the corresponding sulfoxides initiated by a visible-light-induced photoredox reaction of V10. As for the formation of sulfones, MEK-derived peroxide species as the co-catalysts are probably involved in the oxygenation of sulfoxides to sulfones. The selectivity switch of the V10-photocatalysed reaction brought about by water addition is most likely achieved by suppressing the formation of MEK-derived peroxide species. This journal is

Green oxidations. Manganese(II) sulfate aided oxidations of organic compounds by potassium permanganate

The oxidation of arenes and sulfides by potassium permanganate was accomplished in good yields under solvent free and heterogeneous conditions when manganese(II) sulfate is used as a solid support. After extraction of the organic products, the inorganic products can be reoxidized to permanganate. This result is important because it provides an approach to oxidation reactions that is, in theory, infinitely sustainable. Springer-Verlag 2007.

PHARMACOLOGICALLY ACTIVE COMPOUND AND USE

1-Ethylphenoxathiin 10,10-dioside (I) inhibits monoamine oxidase-A and is useful in the treatment of disorders such as depression.