(1R,2S)-1,2-Diphenyl-2-(methylamino)ethanol

Base Information

Chemical Name:(1R,2S)-1,2-Diphenyl-2-(methylamino)ethanol
CAS No.:550-58-3
Molecular Formula:C15H17NO
Molecular Weight:227.3
Hs Code.:2922199090
Mol file:550-58-3.mol

Synonyms:(1R,2S)-1,2-Diphenyl-2-(methylamino)ethanol;[1R,2S,(-)]-1,2-Diphenyl-2-methylaminoethanol;[αR,βS,(-)]-β-Methylamino-α-phenylbenzeneethanol;erythro-(-)-Ephenamine

Suppliers and Price of (1R,2S)-1,2-Diphenyl-2-(methylamino)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (1R,2S)-1,2-Diphenyl-2-(methylamino)ethanol

Chemical Property:

Melting Point:177 °C (decomp)(Solv: 1,4-dioxane (123-91-1); ethyl ether (60-29-7))
Boiling Point:355.5±9.0 °C(Predicted)
PKA:13.70±0.20(Predicted)
PSA：32.26000
Density:1.096±0.06 g/cm3(Predicted)
LogP:3.07160

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2S)-1,2-Diphenyl-2-(methylamino)ethanol

There total 77 articles about (1R,2S)-1,2-Diphenyl-2-(methylamino)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.9%

: 1380213-66-0
C₄₇H₅₉ClN₄O₆SSi

: 1380213-60-4
C₂₀H₂₅ClN₂O

: 550-58-3,20616-51-7,20616-52-8,46797-67-5,53176-60-6,54852-85-6,75196-48-4,90365-73-4
(1R,2S)-1,2-diphenyl-2-(N-methyl)aminoethanol

Guidance literature:: C₄₇H₅₉ClN₄O₆SSi; With potassium carbonate; thiophenol; In dimethyl sulfoxide; at 23 ℃; for 3h; Inert atmosphere;

With potassium ethoxide; triethylamine tris(hydrogen fluoride); In ethanol; dimethyl sulfoxide; at 23 - 85 ℃; for 24.1h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1002/anie.201200387

Reference yield: 98.0%

: 301191-47-9
N-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]formamide

: 550-58-3,20616-51-7,20616-52-8,46797-67-5,53176-60-6,54852-85-6,75196-48-4,90365-73-4
(1R,2S)-1,2-diphenyl-2-(N-methyl)aminoethanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at 0 - 23 ℃; for 22.1667h; Inert atmosphere;
DOI:10.1002/anie.201200370