Piperazine, 1-(3-(4-chlorophenoxy)propyl)-4-phenyl-

Base Information

• Chemical Name: Piperazine, 1-(3-(4-chlorophenoxy)propyl)-4-phenyl-
• CAS No.: 84344-35-4
• Molecular Formula: C₁₉H₂₃ClN₂O
• Molecular Weight: 330.857
• Hs Code.: 2933599090
• DSSTox Substance ID: DTXSID90233305
• Wikidata: Q83114768
• Mol file: 84344-35-4.mol

Synonyms:BRN 4530213;84344-35-4;Piperazine, 1-(3-(4-chlorophenoxy)propyl)-4-phenyl-;1-(3-(4-Chlorophenoxy)propyl)-4-phenylpiperazine;DTXSID90233305;LS-111195

Chemical Property of Piperazine, 1-(3-(4-chlorophenoxy)propyl)-4-phenyl-

Chemical Property:

• Vapor Pressure: 2.66E-09mmHg at 25°C
• Boiling Point: 478°C at 760 mmHg
• Flash Point: 242.9°C
• PSA: 15.71000
• Density: 1.152g/cm³
• LogP: 3.93400
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 330.1498911
• Heavy Atom Count: 23
• Complexity: 319

Purity/Quality:

PIPERAZINE, 1-(3-(4-CHLOROPHENOXY)PROPYL)-4-PHENYL- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(CCN1CCCOC2=CC=C(C=C2)Cl)C3=CC=CC=C3

Technology Process of Piperazine, 1-(3-(4-chlorophenoxy)propyl)-4-phenyl-

There total 2 articles about Piperazine, 1-(3-(4-chlorophenoxy)propyl)-4-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-phenyl-1-piperazine (92-54-6) → 1-[3-(4-Chloro-phenoxy)-propyl]-4-phenyl-piperazine (84344-35-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / 25percent KOH / acetone / 8 h

2: NaOH / ethanol; H₂O / Heating

With potassium hydroxide; sodium hydroxide; In ethanol; water; acetone;

Reference yield:

1-(3-chloropropyl)-4-phenylpiperazine (10599-17-4) + 4-chloro-phenol (106-48-9,82344-39-6) → 1-[3-(4-Chloro-phenoxy)-propyl]-4-phenyl-piperazine (84344-35-4)

Guidance literature:

With sodium hydroxide; In ethanol; water; Yield given; Heating;

upstream raw materials:

1-(3-chloropropyl)-4-phenylpiperazine

4-chloro-phenol

4-phenyl-1-piperazine

Refernces