meso-2,3-Diphenylsuccinic acid

Base Information

• Chemical Name: meso-2,3-Diphenylsuccinic acid
• CAS No.: 1225-13-4
• Molecular Formula: C₁₆H₁₄O₄
• Molecular Weight: 270.285
• Hs Code.: 2917399090
• European Community (EC) Number: 214-953-7,659-979-3
• NSC Number: 75627
• DSSTox Substance ID: DTXSID601275979
• Nikkaji Number: J135.958D
• ChEMBL ID: CHEMBL1991958
• Mol file: 1225-13-4.mol

Synonyms:meso-2,3-Diphenylsuccinic acid;1225-13-4;(2r,3s)-2,3-diphenylsuccinic acid;(2S,3R)-2,3-diphenylbutanedioic acid;trans-2,3-Diphenylsuccinic acid;NSC75627;Butanedioic acid, 2,3-diphenyl-, (2R,3S)-rel-;(2R,3S)-2,3-diphenylbutanedioic acid;EINECS 214-953-7;NSC-75627;(R*,S*)-2,3-Diphenylsuccinic acid;Butanedioic acid, 2,3-diphenyl-, (R*,S*)-;CHEMBL1991958;SCHEMBL11315838;DTXSID601275979;meso-2,3-Diphenylbutanedioic Acid;Succinic acid,3-diphenyl-, meso-;BAA22513;MFCD00198082;Succinic acid, 2,3-diphenyl-, meso-;NCI60_041658;Butanedioic acid,3-diphenyl-, (R*,S*)-;rel-(2R,3S)-2,3-Diphenylbutanedioic acid;CS-0442963;D2209;T70157;.alpha.-D-Glucopyranoside, methyl 4,6-O-(phenylmethylene)-, cyclic carbonothioate

Chemical Property of meso-2,3-Diphenylsuccinic acid

Chemical Property:

• Vapor Pressure: 8.13E-06mmHg at 25°C
• Melting Point: 248 - 252 °C (ethanol)
• Boiling Point: 360.2°Cat760mmHg
• Flash Point: 185.8°C
• PSA: 74.60000
• Density: 1.307g/cm³
• LogP: 2.72320
• Water Solubility.: Insoluble in water
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 270.08920892
• Heavy Atom Count: 20
• Complexity: 306

Purity/Quality:

98%,99%, ^*data from raw suppliers

meso-2,3-Diphenylsuccinic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C(C2=CC=CC=C2)C(=O)O)C(=O)O
• Isomeric SMILES: C1=CC=C(C=C1)[C@H]([C@H](C2=CC=CC=C2)C(=O)O)C(=O)O

Technology Process of meso-2,3-Diphenylsuccinic acid

There total 101 articles about meso-2,3-Diphenylsuccinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium phenylacetate (114-70-5) → meso-2,3-diphenylsuccinic acid (7584-72-7,21037-34-3,41915-64-4,47039-46-3,74431-38-2,1225-13-4) + MANDELIC ACID (611-71-2,611-72-3,17199-29-0,90-64-2)

Guidance literature:

With diethyl ether; isopropylmagnesium bromide; anschliessend Behandeln mit Sauerstoff;

Reference yield:

isopropylmagnesium bromide (920-39-8) + sodium phenylacetate (114-70-5) → 2-bromophenylacetic acid (4870-65-9,31302-84-8) + meso-2,3-diphenylsuccinic acid (7584-72-7,21037-34-3,41915-64-4,47039-46-3,74431-38-2,1225-13-4)

Guidance literature:

With bromine;

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + 3-(4-dimethylamino-phenylimino)-4,5-diphenyl-cyclopentane-1,2-dione → meso-2,3-diphenylsuccinic acid (7584-72-7,21037-34-3,41915-64-4,47039-46-3,74431-38-2,1225-13-4) + 4-amino-N,N-dimethylaniline (99-98-9)

Guidance literature:

at 130 - 140 ℃;

upstream raw materials:

2-bromophenylacetic acid

(E)-1,2-diphenyl-ethene

diethyl ether

bibenzyl-α,α'-diyl dipotassium

Downstream raw materials:

dimethyl α,α'-diphenylsuccinate

meso-2,3-diphenylsuccinic acid dimethyl ester

3,4-diphenyl-1-propyl-pyrrolidine-2,5-dione

meso-2,3-diphenyl-succinic acid monoethyl ester