(S)-1-(3-CHLOROPHENYL)ETHANAMINE

Base Information

Chemical Name:(S)-1-(3-CHLOROPHENYL)ETHANAMINE
CAS No.:1213318-20-7
Molecular Formula:C₈H₁₀ClN*ClH
Molecular Weight:192.088
Hs Code.:
Mol file:1213318-20-7.mol

Synonyms:

Suppliers and Price of (S)-1-(3-CHLOROPHENYL)ETHANAMINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (S)-1-(3-CHLOROPHENYL)ETHANAMINE

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-1-(3-CHLOROPHENYL)ETHANAMINE

There total 5 articles about (S)-1-(3-CHLOROPHENYL)ETHANAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1164111-46-9
C₈H₈ClN*ClH

: 1213318-20-7
(S)-1-(3-chlorophenyl)ethanamine hydrochloride

Guidance literature:: With 2,6-bis(3,5-bis(3,7-bis(trifluoromethyl)naphthalen-1-yl)phenyl)-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide; di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate; In tert-butyl methyl ether; methyl cyclohexane; at 20 ℃; for 24h; enantioselective reaction; Inert atmosphere; Molecular sieve;
DOI:10.1055/s-0040-1706413

Reference yield:

: 1164111-46-9
C₈H₈ClN*ClH

: 1167414-90-5
(R)-(+)-1-(3-chlorophenyl)ethylamine hydrochloride

: 1213318-20-7
(S)-1-(3-chlorophenyl)ethanamine hydrochloride

Guidance literature:: With chloro(1,5-cyclooctadiene)rhodium(I) dimer; zhaophos; hydrogen; In isopropyl alcohol; at 25 ℃; for 24h; under 7600.51 Torr; Overall yield = 88%; enantioselective reaction; Inert atmosphere; Glovebox; Autoclave;
DOI:10.1002/anie.201404570

Reference yield:

: 99-02-5
3'-Chloroacetophenone

: 1213318-20-7
(S)-1-(3-chlorophenyl)ethanamine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: isopropylamine; amine transaminase from Silicibacter pomeroyi; pyridoxal 5'-phosphate / aq. phosphate buffer; acetone / pH 7.5 / Enzymatic reaction

2: sodium hydroxide / water; tert-butyl methyl ether

With pyridoxal 5'-phosphate; amine transaminase from Silicibacter pomeroyi; isopropylamine; sodium hydroxide; In aq. phosphate buffer; tert-butyl methyl ether; water; acetone;
DOI:10.1002/ejoc.201800323