4-(4-chlorophenyl)-5,6-dihydro-6,6-dimethyl-2H-Pyran-3-methanol

Base Information

Chemical Name:4-(4-chlorophenyl)-5,6-dihydro-6,6-dimethyl-2H-Pyran-3-methanol
CAS No.:1228783-98-9
Molecular Formula:C₁₄H₁₇ClO₂
Molecular Weight:252.741
Hs Code.:
Mol file:1228783-98-9.mol

Synonyms:4-(4-chlorophenyl)-5,6-dihydro-6,6-dimethyl-2H-Pyran-3-methanol

Suppliers and Price of 4-(4-chlorophenyl)-5,6-dihydro-6,6-dimethyl-2H-Pyran-3-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 4-(4-chlorophenyl)-5,6-dihydro-6,6-dimethyl-2H-Pyran-3-methanol

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 4-(4-chlorophenyl)-5,6-dihydro-6,6-dimethyl-2H-Pyran-3-methanol

There total 4 articles about 4-(4-chlorophenyl)-5,6-dihydro-6,6-dimethyl-2H-Pyran-3-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1228783-97-8
methyl 4-(4-chlorophenyl)-6,6-dimethyl-5,6-dihydro-2H-pyran-3-carboxylate

: 1228783-98-9
(4-(4-chlorophenyl)-6,6-dimethyl-5,6-dihydro-2H-pyran-3-yl)methanol

Guidance literature:: methyl 4-(4-chlorophenyl)-6,6-dimethyl-5,6-dihydro-2H-pyran-3-carboxylate; With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 4h;

With hydrogenchloride; water; In diethyl ether;

Reference yield:

: 1194-16-7
2,2-dimethyltetrahydropyran-4-one

: 1228783-98-9
(4-(4-chlorophenyl)-6,6-dimethyl-5,6-dihydro-2H-pyran-3-yl)methanol

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / tetrahydrofuran; hexane / 0.5 h / 20 °C

1.2: 4 h / Reflux

2.1: sodium hydride / diethyl ether; mineral oil / 0.5 h / 0 °C

2.2: 20 °C

3.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / toluene / Reflux

4.1: lithium aluminium tetrahydride / diethyl ether / 4 h

With lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride; sodium carbonate; In tetrahydrofuran; diethyl ether; hexane; toluene; mineral oil;

Reference yield:

: 1228386-26-2
methyl 6,6-dimethyl-4-oxotetrahydro-2H-pyran-3-carboxylate

: 1228783-98-9
(4-(4-chlorophenyl)-6,6-dimethyl-5,6-dihydro-2H-pyran-3-yl)methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / diethyl ether; mineral oil / 0.5 h / 0 °C

1.2: 20 °C

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / toluene / Reflux

3.1: lithium aluminium tetrahydride / diethyl ether / 4 h

With lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride; sodium carbonate; In diethyl ether; toluene; mineral oil;