5α-Cholestane-3β,6α,7α-triol

Base Information

• Chemical Name: 5α-Cholestane-3β,6α,7α-triol
• CAS No.: 56588-31-9
• Molecular Formula: C27H48O3
• Molecular Weight: 420.67
• Mol file: 56588-31-9.mol

Synonyms:5α-Cholestantriol-(3β.6α.7α);3β.6α.7α-Trihydroxy-10.13-dimethyl-17β-((R)-1.5-dimethyl-hexyl)-5α-gonan;5α-Cholestan-3β,6α,7α-triol;(10R)-3c.6t.7t-Trihydroxy-10r.13c-dimethyl-17c-((R)-1.5-dimethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthren;(3S,5S,6R,7S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthrene-3,6,7-triol;

Chemical Property of 5α-Cholestane-3β,6α,7α-triol

Chemical Property:

• Melting Point: 213.5 - 214.5 °C (acetone)
• PSA: 60.69000
• LogP: 5.41020

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5α-Cholestane-3β,6α,7α-triol

There total 2 articles about 5α-Cholestane-3β,6α,7α-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3β-acetoxy-5α-cholest-6-ene (987-53-1) → 5α-cholestane-3β,6α,7α-triol (56588-31-9)

Guidance literature:

With pyridine; osmium(VIII) oxide; diethyl ether; Behandeln unter Lichtausschluss und Kochen des Reaktionsprodukts in Aethanol mit wss. Na₂SO₃-Loesung;

DOI:10.1038/164317a0

Reference yield:

pyridine (110-86-1) + diethyl ether (60-29-7,927820-24-4) + 3β-acetoxy-5α-cholest-6-ene (987-53-1) → 5α-cholestane-3β,6α,7α-triol (56588-31-9)

Guidance literature:

at 20 ℃; Behandeln unter Lichtausschluss und Kochen des Reaktionsprodukts mit wss.-aethanol. Na₂SO₃-Loesung;

DOI:10.1021/ja01528a055 DOI:10.1021/ja01161a019

Reference yield:

pyridine (110-86-1) + 5α-cholestane-3β,6α,7α-triol (56588-31-9) + 4-nitro-benzoyl chloride (122-04-3) → 3β.6α.7α-tris-(4-nitro-benzoyloxy)-5α-cholestane

Guidance literature:

DOI:10.1038/164317a0

upstream raw materials:

3β-acetoxy-5α-cholest-6-ene

pyridine

diethyl ether