(S)-(+)-3-hydroxy-4,4,4-trichlorobutyric beta-lac

Base Information

Chemical Name:(S)-(+)-3-hydroxy-4,4,4-trichlorobutyric beta-lac
CAS No.:16493-63-3
Molecular Formula:C₄H₃Cl₃O₂
Molecular Weight:189.426
Hs Code.:
Mol file:16493-63-3.mol

Synonyms:(S)-(+)-3-Hydroxy-4,4,4-trichlorobutyric β-lactone

Suppliers and Price of (S)-(+)-3-hydroxy-4,4,4-trichlorobutyric beta-lac

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (S)-(+)-3-hydroxy-4,4,4-trichlorobutyric beta-lac

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-(+)-3-hydroxy-4,4,4-trichlorobutyric beta-lac

There total 3 articles about (S)-(+)-3-hydroxy-4,4,4-trichlorobutyric beta-lac which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 75-87-6
chloral

: 75-36-5
acetyl chloride

: 16493-63-3,16493-62-2,20710-33-2
(R)-(-)-3-hydroxy-4,4,4-trichlorobutyric β-lactone

Guidance literature:: With quinindine; N-ethyl-N,N-diisopropylamine; In diethyl ether; at -15 ℃; for 3h; Inert atmosphere;
DOI:10.1016/j.tet.2012.04.107

Reference yield:

: 463-51-4
Ketene

: 75-87-6
chloral

: 16493-63-3,16493-62-2,20710-33-2
(R)-(-)-3-hydroxy-4,4,4-trichlorobutyric β-lactone

: 20710-34-3,16493-62-2,20710-33-2
(S)-3-hydroxy-4,4,4-trichlorobutyric β-lactone

Guidance literature:: With Quinine; In toluene; at -50 ℃; Product distribution; other chiral reagents;
DOI:10.1021/ja00365a030

Reference yield:

: 75-87-6
chloral

: 75-36-5
acetyl chloride

: 16493-63-3,16493-62-2,20710-33-2
(R)-(-)-3-hydroxy-4,4,4-trichlorobutyric β-lactone

: 20710-34-3,16493-62-2,20710-33-2
(S)-3-hydroxy-4,4,4-trichlorobutyric β-lactone

Guidance literature:: With quinindine; N-ethyl-N,N-diisopropylamine; In diethyl ether; at -15 ℃; optical yield given as %ee; Inert atmosphere;
DOI:10.1002/chem.200902896